A low cost Ti–Si intermetallic compound membrane with nano-pores was successfully prepared by an in-situ reactive sintering process. The all synthesized membrane shows the presence of Ti, Ti5Si3, TiSi and TiO2 phases, and the Ti:Si atomic ratio of membrane is about 1.9. Two different synthesized granule configuration zones on membrane are observed. Membrane synthesized on the surface of Ti particles contains the mean sizes of both 631 nm nano-particles and 238 nm nano-pores, which is considerably different from that of membrane growing on top of the micro-pores of Ti matrix, 238 nm nano-particles and 80 nm nano-pores, respectively.