Self-curing membranes of chitosan/PAA IPNs obtained by radical polymerization: preparation, characterization and interpolymer complexation

Péniche, Carlos; Argüelles‐Monal, Waldo; Davidenko, Natalia; Sastre, R.; Gallardo, Alberto; Román, Julio San

doi:10.1016/s0142-9612(99)00048-4

Cited by 263 publications

(176 citation statements)

References 35 publications

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“…The free radical polymerization of AA and AM in the presence of chitosan results in a hydrogel in which chitosan chains become grafted with the copolymer [19,24]. The use of the difunctional monomer MBA in the reacting mixture promotes the formation of a tridimensional interpenetrated polymer network reinforcing the mechanical properties of the hydrogel as well as restraining its swelling capacity [28].…”

Section: Synthesis and Spectral Characterizationmentioning

confidence: 99%

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Interpenetrated Chitosan-Poly(Acrylic Acid-Co-Acrylamide) Hydrogels. Synthesis, Characterization and Sustained Protein Release Studies

Povea¹,

Argüelles‐Monal²,

Cauich-Rodríguez³

et al. 2011

MSA

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Interpenetrated polymer networks of chitosan (CHI), polyacrylic acid (PAA) and polyacrylamide (PAM) were prepared by free radical polymerization. These hydrogels were either washed with double distilled water (CHI/PAA/PAM) A or hydrolyzed with 1M sodium hydroxide (NaOH), (CHI/PAA/PAM) S. Both types of hydrogels were characterized by infrared spectroscopy, microstructural techniques and compressive mechanical testing. Finally, hydrogels were loaded with bovine serum albumin (BSA) and release followed at different pHs. Infrared spectra analysis showed correspondence between hydrogels and monomer feed compositions. Hydrolyzed hydrogels, had increased water content and pH swelling dependence. Compression modulus of swelled hydrolyzed hydrogels decreased with increasing equilibrium water content. Higher BSA loadings were achieved on hydrolyzed hydrogels due to their high water content and porosity. Protein release from hydrogels was low ( 20% after 10 hours) at pH 1.2, but sustained release was observed at pH 6.8 and 7.4. The integrity of the protein released at 6.8 and 7.4 by hydrolyzed hydrogels was unaffected. The hydrogles showed no cytotoxic effects on human skin dermal fibroblasts as determined by MTT assay except for two compositions of (CHI/PAA/PAM) A samples, which after seven days presented a viability lower than 80% respect to the control.

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Section: Synthesis and Spectral Characterizationmentioning

confidence: 99%

“…Of particular interest are those based on the graft polymerization of monomers such as acryl amide [18], acrylic acid [19], N-isopropylacrylamide [20] and N-vinylpyrrolidone [21] onto chitosan. Chitosan, (1,4)-[2-amino-2-deoxy-β-Dglucan] is a deacetylated derivate of chitin, a natural occurring polymer.…”

Section: Introductionmentioning

confidence: 99%

Interpenetrated Chitosan-Poly(Acrylic Acid-Co-Acrylamide) Hydrogels. Synthesis, Characterization and Sustained Protein Release Studies

Povea¹,

Argüelles‐Monal²,

Cauich-Rodríguez³

et al. 2011

MSA

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“…[12][13][14] Chitosan, obtained from deacetylation of chitin, appears to be more useful in biomedical applications and for the dehydration of aqueous solutions than chitin because it has both hydroxyl and amino groups that can be easily modified. 15,16 For it uses, key properties of chitosan are biocompatibility, bioactivity, nonantigenicity, nontoxicity (its degradation products are known natural metabolites), the ability to improve wound healing and/or blood clotting, the ability to absorb liquids and form protective films and coatings, and its selective binding of liquids, which has been used to lower serum cholesterol levels. 17,18 Chitosan is a weak base, with an intrinsic pK a near 6.5, and has a low charge density.…”

Section: Introductionmentioning

confidence: 99%

Swelling behavior of polyelectrolyte complex hydrogels composed of chitosan and hyaluronic acid

Kim

Lee

Kim

2004

J of Applied Polymer Sci

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Polyelectrolyte complex (PEC) hydrogels composed of various weight ratios of chitosan and hyaluronic acid were prepared. The PEC hydrogels were formed by the reaction of the oppositely charged chitosan polymers. The PEC films swelled in water rapidly, reaching equilibrium within 30 min, and exhibited relatively high swelling ratios, 243-322%, at 25°C. The swelling ratio increased with increasing temperature. The transport phenomena of all PEC samples were non-Fickian and diffusion and relaxation controlled. The diffusion coefficients of the PEC films ranged from 2.22 ϫ 10 Ϫ6 to 10.05 ϫ 10 Ϫ6 cm 2 /s. The activation energy of the polyelectrolyte complexes ranged from 37.14 to 54.58 kJ/mol and proved to be hydrophilic.

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“…In general, incorporation of PANI into flexible matrix could result in good processability with the electrical conductivity having the requisite properties like chemical stability toward dopants, thermal stability, and insolubility under readily accessible conditions [10,11]. Chitosan has gained growing interest to prepare semi-interpenetrating chitosan/polyaniline [12][13][14], because of its excellent film-forming ability, good adhesion, biocompatibility, and high mechanical strength. Chitosan is a high molecular weight polysaccharide [15] composed of β(1→4) linked 2-deoxy-2-amino-D-glucopyranose units and β(1→4) linked 2-deoxy-2-acetamido-D-glucopyranose units.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and characterization of electrical conducting chitosan-graft-polyaniline

Tiwari¹,

Singh²,

Marg³

2007

Express Polym. Lett.

104

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Abstract.A mucopolysaccharide, chitosan was grafted with polyaniline through oxidative-radical copolymerization using ammonium persulfate in acidic medium. The grafting conditions were extensively studied by varying grafting parameters. All the findings have been discussed and proposed a plausible mechanism for the graft copolymerization. The representative chitosan-graft-polyaniline (Ch-g-PANI) was characterized using UV-vis, FTIR, TGA, X-ray diffraction and Scanning electron microscopy taking chitosan as reference. Ch-g-PANI exhibited electrical conductivity, which increases with the extent of grafting onto chitosan backbone. Its electrical conductivity is further influenced by pH and showed pH switching electrical conduction behavior when exposed to NN3/HCl vapors. The application of conducting biomaterial such as Ch-g-PANI in the electronic devices especially for the fabrication of sensor devices would be attractive not only in terms of product cost and environmental safety but also from a materials science point of view.

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Self-curing membranes of chitosan/PAA IPNs obtained by radical polymerization: preparation, characterization and interpolymer complexation

Cited by 263 publications

References 35 publications

Interpenetrated Chitosan-Poly(Acrylic Acid-Co-Acrylamide) Hydrogels. Synthesis, Characterization and Sustained Protein Release Studies

Interpenetrated Chitosan-Poly(Acrylic Acid-Co-Acrylamide) Hydrogels. Synthesis, Characterization and Sustained Protein Release Studies

Swelling behavior of polyelectrolyte complex hydrogels composed of chitosan and hyaluronic acid

Synthesis and characterization of electrical conducting chitosan-graft-polyaniline

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