The purpose of this study is to examine how the inmates adapt/adjust to jail environments in the prison, in terms of their physical, physiological, social and psychological well-being. The study is beneficial to the inmates, jail managers, political leaders, fellow researches and nurses. This descriptivecorrelational study includes ninety-six (96) inmates who were selected using systematic random sampling. This study was conducted within the boundaries of the two jails (Provincial Jail and the Bureau of Jail Management and Penology) in Lanao del Sur Province, 9700, Philippines. The study utilized a researcher-made checklist questionnaire. A pilot study, content validation, and test of the reliability of the survey tool were conducted. Using IBM Software Packages for Social Sciences (SPSS) version 5.0, the following statistical formulas were utilized: frequency percentage distribution, weighted mean (x̅), standard deviation (SD), and Cramer's V(φc) correlation. Most of the inmates incarcerated in Lanao del Sur Province were young adults, single, male, Muslims, high school graduates, and were imprisoned for five to ten years. Inmates sometimes used psychological, physicalphysiological, and social activities as their coping mechanism while inside the jail system. Majority of the inmates never experienced problems pertaining to health and economic concerns but sometimes experienced problems concerning psychosocial matters. Cramer's V(φc) revealed a strong correlation between the socio-demographic profiles and coping mechanisms of the inmates. Therefore, nurses assigned in the jail facility face must promote the safety, welfare, and well-being of inmates despite the overcrowding situation in the Philippine jail system.