Purpose: We investigated the effects of a video-based education program for cerebral angiography on patients' state anxiety, uncertainty, nursing care satisfaction, and complications.Methods: The randomized experimental study included patients who underwent cerebral angiography at a university hospital in Bucheon, Gyeonggi-do between January 2023 and August 2023. Patients were assigned to the experimental group (n=50) and the control group (n=48). The program included video- and pamphlet-based education. The intervention included video-based education provided to the experimental group and conventional pamphlet-based education provided to the control group. Data were obtained pre-, post-, and 2–7 days post-intervention. Data were analyzed using the x²-test and the repeated measures analysis of variance test with the SPSS software, version 28.0.Results: The experimental group showed lower levels of state anxiety (x²=4.316, <i>p</i>=.038) and uncertainty (x²=3.974, <i>p</i>=.046) than the control group. However, we observed no significant intergroup differences in satisfaction with nursing care and complication rates.Conclusion: The results suggest that a video-based education program for cerebral angiography can effectively reduce state anxiety and uncertainty in patients undergoing cerebral angiography. Video-aided educational interventions can improve the quality of nursing care with regard to reducing state anxiety and uncertainty in patients who undergo cerebral angiography.