Self-esteem, locus of control, hippocampal volume, and cortisol regulation in young and old adulthood

Pruessner, Jens C.; Baldwin, Mark W.; Dedovic, Katarina; Renwick, Robert; Khalili-Mahani, Najmeh; Lord, Catherine; Meaney, Michael J.; Lupien, Sonia J.

doi:10.1016/j.neuroimage.2005.06.014

Cited by 275 publications

(193 citation statements)

References 47 publications

Supporting

Mentioning

168

Contrasting

Unclassified

Order By: Relevance

“…We also found that both stress and self-esteem were associated with cortisol responses, but not DHEA which is similar to that in other studies of stress and endocrine functioning (Pruessner et al 2005). …”

Section: Discussionsupporting

confidence: 90%

“…Further, given that stress, social support, and self-esteem are important psychological mediators of unemployment stress, health and endocrine function (Segerstrom and Miller 2004, Pruessner et al 2005, Uchino 2006, O'Donnell et al 2008 we also wanted to confirm that our unemployed group were highly stressed and also tested whether they were associated with cortisol and DHEAS responses in these groups.…”

Section: Egerstro a D O Co Ormentioning

confidence: 99%

See 1 more Smart Citation

Unemployment is associated with lower cortisol awakening and blunted dehydroepiandrosterone responses

Gallagher

Sumner

Muldoon

et al. 2016

Psychoneuroendocrinology

View full text Add to dashboard Cite

DisclaimerThe University of Gloucestershire has obtained warranties from all depositors as to their title in the material deposited and as to their right to deposit such material.The University of Gloucestershire makes no representation or warranties of commercial utility, title, or fitness for a particular purpose or any other warranty, express or implied in respect of any material deposited.The University of Gloucestershire makes no representation that the use of the materials will not infringe any patent, copyright, trademark or other property or proprietary rights.The University of Gloucestershire accepts no liability for any infringement of intellectual property rights in any material deposited but will remove such material from public view pending investigation in the event of an allegation of any such infringement. PLEASE SCROLL DOWN FOR TEXT.This is a peer-reviewed, post-print (final draft post-refereeing) version of the following published document:Gallagher, Stephen and Sumner, Rachel C and Muldoon, Orla T and Creaven, AnnMarie andHannigan, Ailish (2016). Unemployment is associated with lower cortisol awakening and blunted dehydroepiandrosterone responses. Psychoneuroendocrinology, 69, 41-49. ISSN 03064530Published in Psychoneuroendocrinology, and available online at:http://www.sciencedirect.com/science/article/pii/S0306453016300725We recommend you cite the published (post-print) version.The URL for the published version is http://dx.doi.org/10.1016/j.psyneuen.2016.03.011 DisclaimerThe University of Gloucestershire has obtained warranties from all depositors as to their title in the material deposited and as to their right to deposit such material.The University of Gloucestershire makes no representation or warranties of commercial utility, title, or fitness for a particular purpose or any other warranty, express or implied in respect of any material deposited.The University of Gloucestershire makes no representation that the use of the materials will not infringe any patent, copyright, trademark or other property or proprietary rights.The University of Gloucestershire accepts no liability for any infringement of intellectual property rights in any material deposited but will remove such material from public view pending investigation in the event of an allegation of any such infringement. PLEASE SCROLL DOWN FOR TEXT AbstractPrevious research has investigated the endocrinological consequences of unemployment as a likely pathway behind chronic stress and negative health outcomes. Despite these early attempts at delineating the neuroendocrine consequences of the chronic stress experienced by the unemployed, identifying a consistent and stable effect has remained elusive. Here we sought to strengthen existing knowledge into the effect of the stress of employment status on cortisol by improving on the methodological weaknesses of earlier studies and extend this line of enquiry by measuring the steroid hormone Dehydroepiandrosterone-Sulfate (DHEAS). Saliva samples were collected from unemployed and employe...

show abstract

Section: Discussionsupporting

confidence: 90%

Section: Egerstro a D O Co Ormentioning

confidence: 99%

Unemployment is associated with lower cortisol awakening and blunted dehydroepiandrosterone responses

Gallagher

Sumner

Muldoon

et al. 2016

Psychoneuroendocrinology

View full text Add to dashboard Cite

show abstract

“…Several mechanisms could account for hippocampal damage in T2DM, among which are, for example, the formation of toxic advanced glycation end-products (Rojas and Morales, 2004), increased production of superoxides via increased intracellular glucose metabolism (Brownlee, 2001), and endothelial dysfunction (Tooke and Hannemann, 2000). This corroborates the findings of two previous reports in healthy young (Pruessner et al, 2007) and older adults (Pruessner et al, 2005) The hippocampus may have a role in the regulation of the HPA axis, which extends beyond the feedback regulation of the axis (de Kloet, 2000 andHerman et al, 2005). Studies on HPA axis have focused on the hippocampus as a regulatory entity with a negative feedback function or as a target structure for cortisol, and have generally yielded negative associations between hippocampal volume and cortisol levels (smaller volumes associated with higher cortisol levels).…”

Section: Wwwintechopencomsupporting

confidence: 89%

The Bidirectional Relationship Between Psychiatry and Type 2 Diabetes Mellitus

Rabie¹

2011

Topics in the Prevention, Treatment and Complications of Type 2 Diabetes

View full text Add to dashboard Cite

“…Manual segmentation of the hippocampus was performed using a protocol developed by Pruessner et al (2000). This protocol with proven reliability and validity has been implemented in numerous studies of this laboratory (Pruessner et al, 2001(Pruessner et al, , 2005 and benefits from superior visualization of the target structures in all three dimensions (coronal, sagittal, and horizontal).…”

Section: Methodsmentioning

confidence: 99%

Maternal Care Modulates the Relationship between Prenatal Risk and Hippocampal Volume in Women But Not in Men

Buß¹,

Lord²,

Wadiwalla³

et al. 2007

J. Neurosci.

178

115

View full text Add to dashboard Cite

Smaller hippocampal volume is associated with psychiatric disorders. Variations in hippocampal volume are discussed as both a consequence of the neurotoxic effects of stress and as a pre-existing condition leading to increased vulnerability for cognitive and emotional impairments. To investigate whether early experience can account for variability in hippocampal volume in adulthood (vulnerability hypothesis), we assessed the relationship between birth weight and hippocampal volume in 44 subjects. The reported quality of maternal care in early childhood, as evaluated by the Parental Bonding Inventory, was used as index of the quality of the postnatal environment. Hippocampal volume was assessed from magnetic resonance images using a manual segmentation protocol. We show that birth weight significantly predicts hippocampal volume in adulthood only in female subjects reporting low maternal care. The results suggest that the postnatal environment modulates the neurodevelopmental consequences of prenatal risk and that this effect is sex-specific.

show abstract

Self-esteem, locus of control, hippocampal volume, and cortisol regulation in young and old adulthood

Cited by 275 publications

References 47 publications

Unemployment is associated with lower cortisol awakening and blunted dehydroepiandrosterone responses

Unemployment is associated with lower cortisol awakening and blunted dehydroepiandrosterone responses

The Bidirectional Relationship Between Psychiatry and Type 2 Diabetes Mellitus

Maternal Care Modulates the Relationship between Prenatal Risk and Hippocampal Volume in Women But Not in Men

Contact Info

Product

Resources

About