Self mutilation as a feature of Addison's disease.

Rajathurai, A; Chazan, Bibiana; Jeans, J E

doi:10.1136/bmj.287.6398.1027

Cited by 16 publications

(3 citation statements)

References 3 publications

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“…In primary adrenocortical insufficiency (Addison's disease) the reported psychological symptoms include not only apathy, negativism, and loss of interest, but also some degree of irritability and periodic disturbances of temper, activity and drive (27)(28)(29)(30)(31). These symptoms can all be found in violent antisocial personality and in undersocialized aggressive conduct disorder, while only some of the latter are encountered in intermittent explosive disorder.…”

Section: Discussionmentioning

confidence: 95%

Urinary free cortisol secretion in habitually violent offenders

Virkkunen

1985

Acta Psychiatr Scand

196

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Male violent offenders (n = 90) and residivious arsonists (n = 10) were investigated by urinary (24 h) free cortisol measurements at mental examination on a psychiatric department. The measurements were made with competitive protein-binding radioassay. Only among the habitually violent offenders with antisocial personality were the values low when compared with other violent offenders, antisocial personality without the habitually violent tendency, and male clinic personnel. Poor motivation already in school, truancy, attention deficit and undersocialized aggressive conduct disorder problems seemed to be connected with the low cortisol levels.

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Section: Discussionmentioning

confidence: 95%

Urinary free cortisol secretion in habitually violent offenders

Virkkunen

1985

Acta Psychiatr Scand

196

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“…More recently, chronic self-mutilation in a 14 year old girl that regressed completely following treatment for previously unsuspected Addison's disease has been described. 12 In man, raised circulating ,B-endorphins occur in association with raised ACTH levels13 suggesting a possible explanation for the observed psychological changes since ,B-endorphin administration is known to produce a neuroleptic-like syndrome in rats.14 Almost invariably anorexia nervosa is associated with hypercortisolism15 due to reduced metabolic clearance of cortisol, and basal plasma ACTH is normal. Nevertheless we cannot entirely discount the possibility that adrenal failure was a consequence of chronic, severe malnutrition in our patient.…”

Section: Discussionmentioning

confidence: 99%

Addison’s disease presenting as anorexia nervosa in a young man

Tobin

Morris

1988

Postgraduate Medical Journal

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Summary:A young man with a long history of obsessional traits and food fads presented with anorexia, vomiting and marked weight loss. He showed little concern for his physical state and his vomiting was frequently witnessed as self-induced. A diagnosis of anorexia nervosa was made and he took his own discharge from hospital. He was readmitted one month later, severely cachectic and with biochemical abnormalities consistent with advanced Addison's disease which was subsequently confirmed. He responded dramatically, both mentally and physically, to corticosteroid therapy. It is likely that anorexia nervosa, relatively rare in males, was a manifestation of the psychological abnormalities commonly seen in severe Addison's disease.

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“…Six more recent reports support the association between depression and hypercortisolism. Cohen 48], where inhibitory behavior prevailed [47], In adults, however, depression is a common manifestation. In the majority of cases described by McFarland [44], psychotic symptoms were associated with complica tions such as electrolyte disturbances, hypo glycemia and convulsions.…”

Section: Cushing's Syndromementioning

confidence: 99%

Psychosomatic View of Endocrine Disorders

Fava

Sonino²,

Morphy³

1993

Psychother Psychosom

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This review is concerned with the clinical and research implications of psychosomatic research in endocrinology. A possible role of life events in the pathogenesis of endocrine disease, the psychological distress associated with acute illness, and the issue of quality of life in clinical endocrinology are surveyed. In particular, the psychosomatic aspects of Cushing’s syndrome, Addison’s disease, hyperthyroidism, hypothyroidism, hyperprolactinemia, acromegaly, growth hormone deficiency, and hirsutism are considered.

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Self mutilation as a feature of Addison's disease.

Cited by 16 publications

References 3 publications

Urinary free cortisol secretion in habitually violent offenders

Urinary free cortisol secretion in habitually violent offenders

Addison’s disease presenting as anorexia nervosa in a young man

Psychosomatic View of Endocrine Disorders

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