Chronic pain often interferes with daily functioning, and may become a threat to an individual's sense of self. Despite the development of a recent theoretical account focussing upon the relationship between the presence of chronic pain and a person's self, research investigating this idea is limited. In the present study we aimed to (1) compare the strength of association between self-and pain schema in chronic pain patients and healthy control subjects and (2) research whether the strength of association between self-and pain schema is related to particular pain-related outcomes and individual differences of chronic pain patients. Seventy three chronic pain patients (M age =49.95; SD=9.76) and 53 healthy volunteers (M age =48.53; SD=10.37) performed an Implicit Association Test (IAT) to assess the strength of association between pain-and self-schema.Chronic pain patients also filled out self-report measures of pain severity, pain suffering, disability, depression, anxiety, acceptance and helplessness. Results indicated that the pain-and self-schema were more strongly associated in chronic pain patients than in healthy control subjects. Second, results indicated that, in chronic pain patients, a stronger association between self-and pain schema, as measured with the IAT, is related to a heightened level of pain severity, pain suffering, anxiety and helplessness. Current findings give first support for the use of an IAT to investigate the strength of association between self-and pain schema in chronic pain patients and suggest that pain therapies may incorporate techniques that intervene on the level of self-pain enmeshment.