Background: It's necessary to conduct meta-analysis to quantitatively evaluate the effect and safety of highintensity interval training (HIIT) on obese adolescents, to provide a basis for the management of obesity in adolescents.Methods: Randomized controlled trials (RCTs) on the role of HIIT in the obese adolescents were searched from PubMed databases and so on up to Jan 15, 2021. Two researchers independently performed literature screening, literature quality evaluation and data extraction according to the inclusion and exclusion criteria.Revman 5.3 Software and Stata 12.2 Software were used for data analysis.