Self-perceived sensory responses to soap and synthetic detergent bars correlate with clinical signs of irritation

Simion, Francesca; Rhein, Linda D.; Morrison, Boyce M; Scala, Diana D.; Salko, Diane M; Kligman, Albert M.; Grove, Gary L.

doi:10.1016/0190-9622(95)90127-2

Cited by 75 publications

(54 citation statements)

References 13 publications

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“…While various attempts have been made to establish an objective means of substantiating patient accounts, there have not been satisfying solutions. Subjective methods include LAST, 19 the washing challenge test, 20 and burning induction test using chloroform ⁄ methanol solution. 21 Objective methods include measuring the EI or TEWL by applying sodium lauryl sulfate, 22 the erythema and wheal induction test using dimethylsulfoxide 23 and measuring the blistering time after applying ammonium hydroxide on the skin.…”

Section: -17mentioning

confidence: 99%

Quantitative study of stratum corneum ceramides contents in patients with sensitive skin

Cho

Chung

Lee

et al. 2011

The Journal of Dermatology

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People with sensitive skin (SS) are those who state their skin is more sensitive than that of average persons. The stratum corneum is responsible for maintaining skin barrier function. Ceramides, major constituents of stratum corneum lipids, have been shown to predominantly contribute to the role. It has been suggested that barrier function in SS is decreased. However, we could find very few reports about stratum corneum ceramides in SS. This study was done to find out differences in stratum corneum ceramides between SS and non-SS groups. Fifty individuals (20 with SS and 30 with non-SS) were recruited. Lactic acid sting test (LAST) was performed on the left cheek. On six sites including the right cheek, arm, thigh, leg, back and palm, transepidermal water loss (TEWL) and erythema index (EI) were measured. On the above six sites, stratum corneum sheets were obtained by stripping with cyanoacrylate resin and stratum corneum lipids were extracted, then, analyzed by high-performance liquid chromatography electrospray ionization mass spectrometry. LAST scores were higher in the SS group, but not statistically significant. There were no differences in TEWL and EI values between the two groups. The mean value of the quantity of stratum corneum ceramides on the face was significantly lower in the SS group. On other sites, mean values were also lower in the SS group, but not statistically significant. The quantity of ceramides was significantly decreased in the face of the SS group compared to that of the non-SS group. These results suggest that the decrease in stratum corneum ceramides on facial skin could be related to SS development.

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Section: -17mentioning

confidence: 99%

Quantitative study of stratum corneum ceramides contents in patients with sensitive skin

Cho

Chung

Lee

et al. 2011

The Journal of Dermatology

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“…Although use of selfassessments by unblinded study participants raises the issue of potential observer bias, self-assessments are worth including in such studies because they can provide information about burning sensation or itching of the skin that cannot be evaluated by objective means. 33 We did not utilize measurements of transepidermal water loss (TEWL), which is considered to be one of the best methods for evaluating skin damage due to chronic irritant contact dermatitis associated with use of soaps and detergents. 3435 However, TEWL measurements are quite susceptible to environmental conditions that might be difficult to control on standard hospital wards.…”

Section: From the Division Of Infectious Diseasesmentioning

confidence: 99%

Using Alcohol for Hand Antisepsis: Dispelling Old Myths

Boyce

2000

Infect. Control Hosp. Epidemiol.

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“…For these reasons, the efficacy of self-reporting questionnaires has been investigated for use among large-scale cohorts. Two previous validation studies have shown the sensitivity and specificity of HD questionnaires to be acceptable (12,13), and a third demonstrated that surveys may also elucidate supplementary information when the skin condition is below a clinically detectable level (14). For these reasons, we considered it necessary to investigate the interactions between the work environment and HD among Chinese hospital nurses using a previouslyvalidated questionnaire survey.…”

Section: Introductionmentioning

confidence: 99%

Work environment and hand dermatitis among nurses in a Chinese teaching hospital

Smith

Wei

Kang

et al. 2004

Environ Health Prev Med

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Objective: The aim of this study was to investigate the effects of the working environment on hand dermatitis (HD) prevalence among nurses in a Chinese teaching hospital.Methods: We utilised a previously validated, self-reporting survey which was translated into Chinese.Results: The prevalence of HD among nurses was 18.3%, although this rate varied between departments, ranging from 9.4% in gynaecology to 26.7% in intensive care (P for Trend=0.3167). Logistic regression indicated that wet work was the most important HD risk factor, with a 9-fold increase (OR 9.0, 95%CI 1.2−74.9, P=0.0342). Allergic disease was also related to HD, with a 4.6-fold increase noted (OR 4.6, 95%CI 1.4−15.0, P=0.0096).Conclusions: Overall, the prevalence of HD among Chinese hospital nurses appears to be less than that of their foreign counterparts. Nevertheless, the burden of this disease does seem to vary with respect to department of employment within the hospital.

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Self-perceived sensory responses to soap and synthetic detergent bars correlate with clinical signs of irritation

Cited by 75 publications

References 13 publications

Quantitative study of stratum corneum ceramides contents in patients with sensitive skin

Quantitative study of stratum corneum ceramides contents in patients with sensitive skin

Using Alcohol for Hand Antisepsis: Dispelling Old Myths

Work environment and hand dermatitis among nurses in a Chinese teaching hospital

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