Self-perception of aging among HIV-positive and HIV-negative participants in the Multicenter AIDS Cohort Study

Nieves-Lugo, Karen; Ware, Deanna; Friedman, M. Reuel; Haberlen, Sabina; Egan, James E.; Ae, Brown; Dakwar, Omar; Plankey, Michael

doi:10.1080/09540121.2019.1668536

Cited by 10 publications

(16 citation statements)

References 41 publications

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“…Additionally, negative self-perception of aging has also been in association with functional limitations ( 26–28 ). Functional limitations are an important component in the definition of frailty and have also been associated with poor health outcomes such as cardiovascular disease and depressive symptoms ( 7 , 26 , 28 , 32 ). Levy ( 25 ) explained that negative age stereotypes can affect physiological pathways which can negatively influence physical functioning and health outcomes.…”

Section: Discussionmentioning

confidence: 99%

“…Age discrepancy was calculated as the difference between subjective age (“What age (years) do you feel most of the time?”) and chronological age. Age discrepancy was categorized into 3 categories: older subjective age (subjective age > chronological age), no age discrepancy (subjective age = chronological age), and younger subjective (subjective age < chronological age) ( 22 , 24 , 32 ). Aging satisfaction was assessed using the Attitudes Towards Aging subscale from the validated Philadelphia Geriatric Center Morale Scale ( 33–35 ).…”

Section: Methodsmentioning

confidence: 99%

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Negative Perception of Aging Is Associated With Frailty Transitions Within a Cohort of Sexual Minority Men

Nieves-Lugo

Ware

Althoff

et al. 2021

Innovation in Aging

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Background and Objectives Older people have increased risk of developing frailty, an age-related clinical syndrome associated with worse health outcomes. This study examined the effect of self-perception of aging (i.e., age discrepancy - individuals feel younger/older than their chronological age, and aging satisfaction) on frailty transitions. Research Design and Methods We use longitudinal data from 549 HIV-/499 HIV+ sexual minority men (SMM) aged 50 years or older enrolled in the Multicenter AIDS Cohort Study (MACS). To test the association of self-perception of aging on transitions between states of frailty (non-frail/frail), defined using Fried Frailty Phenotype, a multinomial modeling was used. Results With remaining non-frail as the referent group, participants reporting low aging satisfaction (vs moderate aging satisfaction) had increased odds of transitioning from Non-Frail to Frail (OR: 2.72; 95% CI:1.56-4.74), Frail to Non-Frail (OR: 3.40; 95% CI: 1.62-7.12) or remaining frail (Frail to Frail) (OR: 6.64; 95% CI: 3.88-11.38). Participants reporting older subjective age (vs no age discrepancy) had increased odds of transitioning from Non-Frail to Frail (OR: 2.50; 95% CI: 1.11-5.64), Frail to Non-Frail (OR: 4.47; 95% CI: 1.85-10.81) or remaining frail (Frail to Frail) (OR: 5.68; 95% CI: 3.06-10.56). High aging satisfaction and younger subjective age were not statistically associated with frailty transitions. Discussion and Implications Our findings show that negative self-perception of aging (i.e., older subjective age and low aging satisfaction) is associated with frailty transitions (non-frail to frail, frail to non-frail, frail to frail) when compared to remaining non-frail. Translational significance Frailty is associated with increased risk of adverse health outcomes and poor quality of life. Independent of HIV-status, negative self-perception of aging (i.e., low aging satisfaction and older subjective age) is associated with frailty transitions among a cohort of sexual minority men aged 50 years or older. Given functional limitations are a core component of the definition of frailty, promoting efforts that would mitigate the impact of negative self-perceptions of aging on functional limitations is important. The impact of this individual level factor will intersect with other dyadic, community and structural factors, all of which foster healthy aging.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Negative Perception of Aging Is Associated With Frailty Transitions Within a Cohort of Sexual Minority Men

Nieves-Lugo

Ware

Althoff

et al. 2021

Innovation in Aging

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“…Nieves-Lugo et al found that having symptoms of depression was associated with poor age satisfaction and older subjective age with MACS participants. 2 Given the relationships between subjective age and depression, it seems that HIV status paired with having an older subjective age plays a central role in a person's mental health outcome of depression.…”

Section: Georgetown Medical Reviewmentioning

confidence: 99%

“…Having older subjective age has been positively associated with being HIVpositive and having less than a high school education, depressive symptoms, diabetes, and medium and low aging satisfaction. 2 To our knowledge, there is no literature exploring the association between subjective aging and depression among people living with HIV. Therefore, data from the MACS was used to understand the role that subjective aging plays on depression among people who are living with and without HIV.…”

Section: Georgetown Medical Reviewmentioning

confidence: 99%

“…One perspective to address feeling older can be found in the work of Nieves-Lugo et al when they described how physical health and lifestyle factors influence self-perceptions of aging. 2 The perception of the importance someone internally holds regarding their contribution to their external environment is called mattering. 19,20,38 We postulate that aging could result in decreasing a person's outlook on mattering and could subsequently stimulate depressive symptoms.…”

Section: Georgetown Medical Reviewmentioning

confidence: 99%

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Association Between Subjective Age and Depressive Symptoms Among Middle-Aged and Aging HIV-Positive and HIV-Negative Men in the Multicenter AIDS Cohort Study

Blade

Ware

Plankey

2022

Georgetown Medical Review

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Introduction Older subjective age, or felt age, has been positively associated with being HIV-positive and having less than a high school education, depressive symptoms, diabetes, and medium and low aging satisfaction. To our knowledge, there is no literature exploring the association between subjective aging and depression among people living with HIV. Data from the Multicenter AIDS Cohort Study (MACS) was used to understand the role that subjective aging plays on depression among people who are living with and without HIV. We hypothesized that feeling older will be negatively associated with presenting symptoms of depression among men living with HIV compared to men living without HIV following an adjustment to the model to control for covariates. Methods The MACS is an observational cohort study that follows sexual minority men living with and without HIV in four sites within the United States: Baltimore, Maryland/Washington, DC; Chicago, Illinois; Los Angeles, California; and Pittsburgh, Pennsylvania/Columbus, Ohio. MACS participants attend semiannual visits that collect social, behavioral, medical history, and specimens using an Audio Computer-Assisted Self-Interview and standardized clinical examinations. The study design of the MACS has been described elsewhere. From 1984 to 2018, 7,352 men have been enrolled the MACS. 1,118 of these men were included in this study from the MACS substudy, ‘Understanding Patterns of Healthy Aging Among Men Who Have Sex With Men’, which was administered in six waves between March 2016 and September 2019. We used cross-sectional data from October 2016 to April 2017. Odds ratios (including 95% CIs) were generated using logistic regression models to test the association of subjective age with the presence of depressive symptoms (defined as a score >=16 using the Center for Epidemiological Study Depression scale). Odds ratios were adjusted for age, race/ethnicity, educational attainment, smoking status, history of hypertension, renal disease, dyslipidemia, liver disease, diabetes and HIV status. Results After adjusting for covariates, older age discrepancy was associated with higher odds of depressive symptoms (vs younger discrepancy; OR: 4.00; 95% CI: 2.39-6.69). Increasing age (5-year increase; OR: 0.81; 95% CI: 0.72-0.91) was associated with lower odds of depressive symptoms. Lower educational attainment was associated with higher odds of depressive symptoms (less than high school degree vs graduate school; OR: 5.33; 95% CI: 1.96-14.53) (high school vs graduate school: OR: 1.93; 95% CI: 1.10-3.37). There was no statistically significant association of HIV status or other covariates with risk of depressive symptoms. Conclusion Our findings demonstrated a statistically significant positive association between older subjective age (independent of increasing chronological age) and greater risk of depressive symptoms. We also found that having a high school or less than a high school education also increased this risk. Statistical significance was not present based on HIV status or other covariates in the adjusted model. Health care professionals should be aware of their patient’s perception of aging in order to address depressive symptoms related to feeling older. Counteracting a person feeling older can be achieved through exercising regularly, prioritizing preventive care, maintaining a vibrant social life, and having an optimistic attitude on the years ahead of them.

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Older People Living with HIV Were Less Physically Active Than Their Uninfected Counterparts in China: A Matched-Sample Mediation Analysis

et al. 2022

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Self-perception of aging among HIV-positive and HIV-negative participants in the Multicenter AIDS Cohort Study

Cited by 10 publications

References 41 publications

Negative Perception of Aging Is Associated With Frailty Transitions Within a Cohort of Sexual Minority Men

Negative Perception of Aging Is Associated With Frailty Transitions Within a Cohort of Sexual Minority Men

Association Between Subjective Age and Depressive Symptoms Among Middle-Aged and Aging HIV-Positive and HIV-Negative Men in the Multicenter AIDS Cohort Study

Older People Living with HIV Were Less Physically Active Than Their Uninfected Counterparts in China: A Matched-Sample Mediation Analysis

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