2019
DOI: 10.1016/j.nanoen.2019.05.056
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Self-powered, on-demand transdermal drug delivery system driven by triboelectric nanogenerator

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Cited by 114 publications
(118 citation statements)
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“…facilities, which often lead to delayed treatment administration [51][52][53]. W-TENGs can effectively scavenge passive pervasive biomechanical energy from the human body with the assistance of power-management circuits, electrically activate the delivery of therapeutic biochemical molecules, and permit controllable and sustainable drug delivery [54][55][56].…”
Section: The Materials Science Of W-tengsmentioning
confidence: 99%
“…facilities, which often lead to delayed treatment administration [51][52][53]. W-TENGs can effectively scavenge passive pervasive biomechanical energy from the human body with the assistance of power-management circuits, electrically activate the delivery of therapeutic biochemical molecules, and permit controllable and sustainable drug delivery [54][55][56].…”
Section: The Materials Science Of W-tengsmentioning
confidence: 99%
“…(d) Electric-stimulated porous polypyrrole film: self-powered drug delivery system [63]. Reproduced with permission from Elsevier [60,61,63] and American Chemical Society [62]. A gas purification system is shown in Figure 3a [60].…”
Section: Directly Controlling Particlesmentioning
confidence: 99%
“…Self-powered drug delivery is a typical application of particle control in the biomedical field. Ouyang et al reported a self-powered transdermal drug delivery system based on a TENG, as shown in Figure 3 d [ 63 ]. This drug delivery system mainly consisted of a radially arrayed TENG and a drug-loaded porous polypyrrole film.…”
Section: Direct Utilizationmentioning
confidence: 99%
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“…Furthermore, the system achieved prominent tumor treatment effects under a low drug dosage at three levels: a 2D culture of HeLa cells, 3D multicellular spheroids, and tumorbearing nude mice, which demonstrated a promising approach for cancer therapy in the clinic. In 2019, Ouyang et al proposed a self-powered, on-demand transdermal DDS, which consisted of a miniaturized rotary TENG, a power management circuit and transdermal patches (including drug patch and iontophoresis patch electrode) (Ouyang et al, 2019) (Figure 8d). The system can achieve an actively adjustable drug release rate from 0.05 to 0.25 μg/cm 2 per minute and improve the efficiency of transdermal drug delivery (TDD) by $50%, indicating a prospect of wearable drug delivery device for personalized healthcare.…”
Section: Self-powered Wearable Therapy Systemmentioning
confidence: 99%