“…The fact that photoreceptor depolarization leads to OFF bipolar cell depolarization is an example of a sign-conserving synapse. At light increments, the lack of glutamate closes ionotropic receptors and hyperpolarizes OFF bipolar cells (17). Thus, light decrements hyperpolarize ON bipolar cells and depolarize OFF bipolar cells whereas light increments depolarize ON bipolar cells and hyperpolarize OFF bipolar cells (Fig.…”
Section: Bipolar Cell Signalingmentioning
confidence: 94%
“…In ON bipolar cells, glutamate binds to mGluR6 and closes the cation channel TRPM1, which hyperpolarizes the cell (17). The fact that photoreceptor depolarization, which results in glutamate release, leads to ON bipolar cell hyperpolarization is an example of a sign-inverting synapse.…”
Section: Bipolar Cell Signalingmentioning
confidence: 99%
“…synchronous, asynchronous, or blended, the latter of which is a mixture of synchronous and asynchronous formats (17). Synchronous online learning is geographically independent but time-dependent where all learning takes place simultaneously like a live online classroom accessed from anywhere with internet access (18,19).…”
Section: Modes For Delivering Instructionmentioning
confidence: 99%
“…Similar to adult learners, online learners must also have intrinsic motivation to "control, manage, and plan their learning actions" in "self-regulated learning" (7,17). Self-regulated online learners must champion their independence to achieve academic success.…”
Section: Adult Learning Theory Is Similar To Online Learning Principlesmentioning
confidence: 99%
“…Online learners must take static information and construct their own knowledge and make meaning (10). Online learners remain engaged when they encounter examples or assessments that apply to their every-day lives, which leads to deep learning (17).…”
Section: Adult Learning Theory Is Similar To Online Learning Principlesmentioning
“…The fact that photoreceptor depolarization leads to OFF bipolar cell depolarization is an example of a sign-conserving synapse. At light increments, the lack of glutamate closes ionotropic receptors and hyperpolarizes OFF bipolar cells (17). Thus, light decrements hyperpolarize ON bipolar cells and depolarize OFF bipolar cells whereas light increments depolarize ON bipolar cells and hyperpolarize OFF bipolar cells (Fig.…”
Section: Bipolar Cell Signalingmentioning
confidence: 94%
“…In ON bipolar cells, glutamate binds to mGluR6 and closes the cation channel TRPM1, which hyperpolarizes the cell (17). The fact that photoreceptor depolarization, which results in glutamate release, leads to ON bipolar cell hyperpolarization is an example of a sign-inverting synapse.…”
Section: Bipolar Cell Signalingmentioning
confidence: 99%
“…synchronous, asynchronous, or blended, the latter of which is a mixture of synchronous and asynchronous formats (17). Synchronous online learning is geographically independent but time-dependent where all learning takes place simultaneously like a live online classroom accessed from anywhere with internet access (18,19).…”
Section: Modes For Delivering Instructionmentioning
confidence: 99%
“…Similar to adult learners, online learners must also have intrinsic motivation to "control, manage, and plan their learning actions" in "self-regulated learning" (7,17). Self-regulated online learners must champion their independence to achieve academic success.…”
Section: Adult Learning Theory Is Similar To Online Learning Principlesmentioning
confidence: 99%
“…Online learners must take static information and construct their own knowledge and make meaning (10). Online learners remain engaged when they encounter examples or assessments that apply to their every-day lives, which leads to deep learning (17).…”
Section: Adult Learning Theory Is Similar To Online Learning Principlesmentioning
This article describes a set of differentiated strategies for supporting the needs of online learners. Ways to combine technological tools with self‐directed learning supports are explained.
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