Background:
Gait disruption is a common poststroke problem. Robot-assisted gait training
(RAGT) might improve motor function, balance, and activities of daily
living.
Objective:
We compared the clinical effectiveness of early integrated RAGT using the
Walkbot robotic gym with an intensity-matched enhanced lower limb therapy
(ELLT) program and with conventional rehabilitation therapy (CRT) in
patients with acute ischemic stroke.
Methods:
A total of 192 patients with acute ischemic stroke were randomly assigned
(1:1:1) to receive RAGT, ELLT, or CRT. All three groups received 45 min of
training daily, 3 days a week, for 4 weeks consecutively. Before and after
the 4-week treatment, the patients were assessed based on a 6-minute walking
test (6MWT), functional ambulation classification (FAC), timed up and go
(TUG) test, dual-task walking (DTW) test, Tinetti’s test, Barthel’s index
(BI), stroke-specific quality of life (SS-QOL) scale, and gait analysis
parameters.
Results:
After the 4-week intervention, the results of the 6MWT, FAC, TUG, DTW,
Tinetti’s test, BI, SS-QOL, and gait in the three groups significantly
improved. Compared with ELLT and CRT groups, participants in the RAGT group
had a better performance in 6MWT (199.11 ± 60.72
versus
182.47 ± 59.72
versus
173.69 ± 40.58,
p
= 0.035), FAC (4.10 ± 0.91
versus
3.69 ± 0.88
versus
3.58 ± 0.81,
p
= 0.044), DTW (10.29 ± 2.38
versus
12.92 ± 2.64
versus
13.89 ± 2.62,
p
= 0.031), SS-QOL (184.46 ± 20.53
versus
165.39 ± 20.49
versus
150.72 ± 20.59,
p
= 0.012), velocity (0.66 ± 0.22
versus
0.55 ± 0.23
versus
0.51 ± 0.20,
p
= 0.008), cycle duration (1.38 ± 0.40
versus
1.50 ± 0.38
versus
1.61 ± 0.30,
p
= 0.040), and swing phase symmetry ratio (SPSR,
1.10 ± 0.33
versus
1.21 ± 0.22
versus
1.48 ± 0.25,
p
= 0.021). The TUG, Tinetti’s test, BI, and
RMT results were similar, however.
Conclusion:
In the acute stroke phase, early integrated RAGT showed greater performance
in gait rehabilitation than CRT and ELLT.
Registration:
ChiCTR1900026225