Self‐report quality of life as a predictor of hospitalization for patients with LV dysfunction: A life course approach¶

Stull, Donald E.; Clough, Lynn; Dussen, Daniel Van

doi:10.1002/nur.10006

Cited by 43 publications

(37 citation statements)

References 43 publications

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“…Our data showed no difference in the average HRQoL scores nor NYHA classification between those aged b 65 years versus ≥ 65 years. The current literature indicates that poor HRQoL is related to higher frequencies of hospital readmission [4][5][6] and death [4,6,7] in non-structured, routine care of HF patients. To the best of our knowledge, this is the first report that demonstrates that HRQoL predicts outcome in patients' followed-up in a DMP.…”

Section: Discussionmentioning

confidence: 99%

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Quality of life predicts outcome in a heart failure disease management program

O’Loughlin

Murphy

Conlon

et al. 2010

International Journal of Cardiology

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Background: Chronic heart failure (HF) is associated with a poor Health Related Quality of Life (HRQoL). HRQoL has been shown to be a predictor of HF outcomes however, variability in the study designs make it difficult to apply these findings to a clinical setting. The aim of this study was to establish if HRQoL is a predictor of long-term mortality and morbidity in HF patients followed-up in a disease management program (DMP) and if a HRQoL instrument could be applied to aid in identifying high-risk patients within a clinical context. Methods: This is a retrospective analysis of HF patients attending a DMP with 18 ± 9 months follow-up. Clinical and biochemical parameters were recorded on discharge from index HF admission and HRQoL measures were recorded at 2 weeks post index admission. Results: 225 patients were enrolled into the study (mean age = 69 ± 12 years, male = 61%, and 78% = systolic HF). In multivariable analysis, all dimensions of HRQoL (measured by the Minnesota Living with HF Questionnaire) were independent predictors of both mortality and readmissions particularly in patients b 80 years. A significant interaction between HRQoL and age (Total (HRQoL) ⁎ age: p b 0.001) indicated that the association of HRQoL with outcomes diminished as age increased.Conclusions: These data demonstrate that HRQoL is a predictor of outcome in HF patients managed in a DMP. Younger patients (b 65 years) with a Total HRQoL score of ≥50 are at high risk of an adverse outcome. In older patients ≥ 80 years HRQoL is not useful in predicting outcome.

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Section: Discussionmentioning

confidence: 99%

“…In patients with HF, poor HRQoL is associated with higher frequencies of hospital readmission [4][5][6] and death [4,6,7]. Furthermore, there is evidence to suggest that HRQoL is poorer in younger HF patients when compared to older patients [8].…”

Section: Introductionmentioning

confidence: 99%

Quality of life predicts outcome in a heart failure disease management program

O’Loughlin

Murphy

Conlon

et al. 2010

International Journal of Cardiology

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“…Thus, impaired HRQOL has been incriminated for cardiovascular disorders as well as increased incidence of death and hospitalization [30,31,32,33]. It has been shown that lower scores in the three major components of HRQOL are strongly associated with a higher risk of death and hospitalization, independent of demographic and comorbid factors in hemodialysis patients [13,34].…”

Section: Discussionmentioning

confidence: 99%

Adaptation and Validation of the Kidney Disease Quality of Life-Short Form Questionnaire in the Greek Language

Malindretos

Sarafidis

Spaia³

et al. 2009

Am J Nephrol

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Aim: The aim of this study was to examine the validity, reproducibility and internal consistency of a Greek translation of the Kidney Disease Quality of Life-Short Form (KDQOL-SF) questionnaire. Methods: The KDQOL-SF questionnaire was translated from English to Greek and was administered in 240 randomly selected patients undergoing hemodialysis in six Renal Units in Greece. The instrument’s validity was tested by examining the association between patient’s KDQOL-SF scores and comorbidity assessed with the Index of Coexistent Disease. Reproducibility was examined by readministering the questionnaire in 50 randomly selected patients within 1 month. Internal consistency was assessed by estimating Cronbach’s alpha coefficient. Results: Patients were divided into two groups according to the severity of comorbidity assessed with the Index of Coexistent Disease. Those with less comorbid conditions had significantly higher scores in most components of the KDQOL-SF questionnaire, confirming its validity. The correlation coefficients between the two administrations of the instrument ranged from 0.88 to 0.98 for each of the main components, which was above the desired level of 0.85. Cronbach’s alpha coefficient ranged from 0.91 to 0.92 for the various components, values well above the minimum desired 0.70 level. Conclusions: The present study shows that the Greek version of the KDQOL-SF questionnaire has high validity, reproducibility and internal consistency. Production of validated translations of the KDQOL-SF questionnaire in various languages will help promote health-related quality of life of end-stage renal disease patients all over the world.

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“…Another marker of poor outcome among dialysis patients is impaired health-related quality of life (HRQOL) [7,8,9]. HRQOL may also be affected by the clinical manifestations of the disease, the side effects of treatment and relationships of the patients with family members and care providers [10].…”

Section: Introductionmentioning

confidence: 99%

Depression, Quality of Life and Malnutrition-Inflammation Scores in Hemodialysis Patients

Ibrahim¹,

Salamony

2008

Am J Nephrol

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Background: Depression is the most common psychiatric illness in patients with end-stage renal disease (ESRD), and has been associated with increased risk of death, cardiovascular events and hospitalization in a substantial proportion of patients. Impaired quality of life (QoL) has been reported in dialysis patients and is a marker of poor outcome. We aimed to assess the prevalence of depression and QoL status among chronic hemodialysis patients. We explored the relationship between depressive symptoms and poor QoL on the one hand and sociodemographic profile, dialysis adequacy, serum chemistry, malnutrition-inflammation score (MIS) and symptom burden on the other hand. Patients and Methods: 60 chronic hemodialysis patients participated in the study between June and August 2007. They were on thrice-weekly dialysis at the Kasr El-Aini Nephrology and Dialysis Center, Cairo University Hospital. Clinical and sociodemographic data were obtained and their case records were reviewed to obtain laboratory results including hemoglobin, urea reduction ratio, serum albumin, calcium, phosphorus, creatinine and total iron-binding capacity. We used the Beck Depression Inventory (BDI) to assess the severity of depression, and the SF-36 questionnaire to assess QoL in the study group. MIS was used to assess the extent of malnutrition and inflammation complex and total symptom burden was evaluated using the dialysis symptom index (DSI). Results: Mean age was 46.13 ± 16.55 years, with a range of 22–77 years. 20 patients (33.33%) had a BDI score of ≧15. Two patients (3.33%) had a QoL total score of <50, 8 (13.33%) had scores in the range of 50–60, 30 (50%) had scores in the range of 60–70, 12 (20%) had scores of 70–80, and 8 patients (13.3%) had scores in the range of 80–90. Employment was found to significantly affect BDI scores; all patients with BDI scores ≧15 were unemployed. The mean BDI score of unemployed patients was significantly higher than employed patients (13.03 ± 6.27 vs. 8.50 ± 3.51, p = 0.03). Widowed patients had significantly higher BDI and lower F-36 scores compared to single, married and divorced patients (p < 0.05). DSI and MIS showed significant positive correlations with BDI scores (p < 0.05) and significant negative correlations with F-36 scores (p < 0.05). Conclusions: Our results showed a high prevalence of depressive symptoms among the study group that was linked to poor QoL, total symptom burden and malnutrition-inflammation complex.

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Self‐report quality of life as a predictor of hospitalization for patients with LV dysfunction: A life course approach¶

Cited by 43 publications

References 43 publications

Quality of life predicts outcome in a heart failure disease management program

Quality of life predicts outcome in a heart failure disease management program

Adaptation and Validation of the Kidney Disease Quality of Life-Short Form Questionnaire in the Greek Language

Depression, Quality of Life and Malnutrition-Inflammation Scores in Hemodialysis Patients

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