Self‐reported lack of energy or feeling depressed 12 months after treatment in men diagnosed with prostate cancer within a population‐based registry

Abstract

Objective: Feeling depressed and lethargic are common side effects of prostate cancer (PCa) and its treatments. We examined the incidence and severity of feeling depressed and lack of energy in patients in a population based PCa registry. Methods:We included men diagnosed with PCa between 2015 and 2019 in Victoria, Australia, and enrolled in the Prostate Cancer Outcomes Registry. The primary outcome measures were responses to two questions on the Expanded Prostate Cancer Index Composite (EPIC-26) patient reported instrument: problems with feeling depressed and problems with lack of energy 12 months following treatment. We evaluated associations between these and age, cancer risk category, treatment type, and urinary, bowel, and sexual function.

Is There a Difference in the Incidence of Depression between Radiation and Surgical Treatments in Patients with Prostate Cancer?

“…A recent prospective cohort study reported no differences in mental health outcomes according to the treatment strategy used for localized PC [ 14 ]. The most important finding of several previous studies is that older age, poorer health, being unmarried, and poor baseline mental health are highly associated with worse mental health outcomes [ 14 15 16 17 ]. These results are consistent with those of the present study, which reported that old age is the most significant risk factor for the development of depression and other psychiatric diseases.…”