Self-reported oral health, oral hygiene, and oral HPV infection in at-risk women in Ho Chi Minh City, Vietnam

Bui, Thanh Cong; Trần, Lý Thị; Markham, Christine; Huynh, Thuy Thi Thu; Tran, Loi Thi; Pham, Vy; Tran, Quan Minh; Hoang, Ngoc Hieu; Hwang, Lu Yu

doi:10.1016/j.oooo.2015.04.004

Cited by 17 publications

(16 citation statements)

References 25 publications

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“…The aetiology and risk factors of oral and oropharyngeal HPV infection remains controversial; however, past studies have shown that these risk factors include oral sex, multiple sexual partners, poor oral hygiene and immunodeficiency conditions [15,16,17,18,19,20]. Identifying key risk factors may help to improve disease screening processes to identify high-risk individuals for developing OPC which may lead to OPC prevention and improve disease mortality [21]. …”

Section: Introductionmentioning

confidence: 99%

A Pilot Study into the Association between Oral Health Status and Human Papillomavirus—16 Infection

et al. 2017

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Background: Over the next 20 years, oropharyngeal cancers (OPC) will represent the majority of head and neck cancers (HNCs) in the United States. It is estimated that human papillomavirus (HPV) may account for as much as 70% to 80% of OPCs in North America and in certain parts of Europe. It is hence crucial to understand the disease risk factors and natural history of oral HPV infections. We hypothesized that poor oral health (by measures such as poor oral hygiene and periodontal disease) leads to a higher degree of oral HPV-16 infections within a patient cohort from a dental school clinic. This study aims to test this hypothesis and gauge possible disease associations before larger scale studies. Subjects and Methods: 223 participants were recruited in this study from the University of Queensland Dental School clinic. Clinical oral health parameters (such as oral hygiene measures and periodontal disease measurements) have been examined and determined by dental professionals. We have collected oral rinse samples from these volunteers. Results: 10 (4.5%) out of 223 participants were found to have HPV-16 DNA in their oral rinse samples using NB2 endpoint PCR and Sanger sequencing. Within the HPV-16 DNA positive subjects, 7 (70%) and 3 (30%) were associated with poor oral hygiene and periodontal disease, respectively. Conclusion: Our results show a trend towards a positive correlation between oral HPV-16 infection and poor clinical oral health status.

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Section: Introductionmentioning

confidence: 99%

A Pilot Study into the Association between Oral Health Status and Human Papillomavirus—16 Infection

et al. 2017

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“…In Mexican males we obtained a prevalence of 34% while reported data ranged from 10.1% (7) to 20% in male attending in a STD clinic (11). In Mexican female we obtained a prevalence of 36.3%, higher than reported in the 2009-2010 USA National Health Survey: 3.6% (6,9).…”

Section: Discussionmentioning

confidence: 62%

“…We obtained a prevalence of 34.5% for all HPV subtypes. HPV prevalence reported in scientific literature is wide, ranging from 0.67% reported in Chinese (5); 6.9%-16% in Americans (6,), to 24.6% in Vietnamese (7). This data suggest that Mexican population possesses the highest oral HPV prevalence reported.…”

Section: Discussionmentioning

confidence: 83%

“…In the present report most of HPV-infected patients were at fifth and seventh decade of life, agrees to the aforementioned data. It has been suggested that the second peak could arise from reactivation of latent infections associated to age-related loss of immunity (7,9). HPV prevalence is closely associated to number of sexual partners (6,8,10).…”

Section: Discussionmentioning

confidence: 99%

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Prevalence of Human Papilloma Virus in the Oral Cavity of a Mexican Sample

Sanchez¹,

Cepeda²

2016

West Indian Med J

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Objective: To assess the prevalence of oral HPV in a Mexican sample and to establish their possible association to socio-demographical characteristics, habits and/or sexual behavior. Methods: 110 consecutive patients atending in an Oral Medicine and Pathology teaching clinic were orally examined and applied a questionnaire concerning demographical characteristics, habits and sexual behavior. At this moment a cytobrush scraping of buccal mucosa was taken and immediately immersed in 80% ethanol, transported to laboratory and centrifuged to obtain a supernatan. HPV identification was made through immunohistochemistry technique using antibody anti-HPV while confirmation of HPV presence and their typífication was done using MY09/11 and GP5+/6+ PCR technique. Possible associations of socio-demographical and sexual behavior variables with HPV infection were establish usng chi square test (p <0.05; 95%IC). Results: 39 (35.4%) patients were HPV-positive, most of them at their 5th decade of life; 74.3% of HPV-positive were smokers; 43.5% intakes alcoholic beverages and 25.6% were marihuana smokers. Their age of onset of sexual life was at 17 years old (Standar Deviation ±6.64), while 59% were sexually active and 64.1% actually practice oral sex. Statistical association of HPV positive male with oral sex (p 0.01) and with smoke marihuana (p 0.04) was establish. HPV13 was the most common HPV subtype identified; HPV53, HPV45 and HPV11 were identified too. Only Six of 39 HPV-positive patients presents HPV clinical lesion: 4 oral papilloma and 2 condiloma acuminata. Conclusions: Mexican population show high HPV oral infection, specifically male who practice oral sex or smoke marihuana.

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“…Recently, women are reportedly at risk of this infection apart from much susceptible male in places like Vietnam [9]. Some estimates suggest that 70-90% of new oropharyngeal cancers have evidence of HPV [10].…”

Section: Discussionmentioning

confidence: 99%

Oral Carcinoma, HPV Infection, Arsenic Exposure-their Correlation in West Bengal, India

Pal¹,

Raychowdhury²,

Halder³

2016

Otolaryngol (Sunnyvale)

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Objective: The aim is to find out any possible correlation between HPV infection and oral carcinoma along with this metal toxicity. Methods:Ethical clearance for this study was obtained from the Ethics Committee of Vivekananda Institute of Medical Sciences, Ramakrishna Mission Seva Pratishthan. Patients attending our hospital were screened for the presence of oral premalignant and malignant lesions. The subjects were administered a standard questionnaire. The buccal swab and hair samples (107 cases and 50 controls) were collected after obtaining informed consent from all the corresponding subjects, and were analysed for detection of HPV 16 DNA and arsenic level analysis, respectively.Results: 22.5% of malignant samples showed the presence of HPV 16 DNA. 80% of cases showed their arsenic count above the safe limit (0.8 µg/g). Conclusion:A considerable percentage of malignant samples showed the presence of HPV16 DNA, indicating that there may be a correlation between HPV infection and oral malignancy in this population. A higher percentage of cases showing an elevated arsenic count states a possible link between arsenic toxicity and the development of this disease. However, a higher population size and statistical analysis are required for a proper conclusion.

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Self-reported oral health, oral hygiene, and oral HPV infection in at-risk women in Ho Chi Minh City, Vietnam

Cited by 17 publications

References 25 publications

A Pilot Study into the Association between Oral Health Status and Human Papillomavirus—16 Infection

A Pilot Study into the Association between Oral Health Status and Human Papillomavirus—16 Infection

Prevalence of Human Papilloma Virus in the Oral Cavity of a Mexican Sample

Oral Carcinoma, HPV Infection, Arsenic Exposure-their Correlation in West Bengal, India

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