Self-Reported Skin Morbidities and Health-Related Quality of Life: A Population-Based Nested Case-Control Study

Vinding, Gabrielle Randskov; Knudsen, Kim; Ellervik, Christina; Olesen, Anne Braae; Jemec, Gregor B. E.

doi:10.1159/000358009

Cited by 46 publications

(42 citation statements)

References 41 publications

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“…HS influences patients' lives in many ways [15] . HS patients experience several emotional reactions, including anger, sadness, anxiety, and depression.…”

Section: Discussionmentioning

confidence: 99%

Quality of Life and Psychosocial Implications in Patients with Hidradenitis Suppurativa

et al. 2016

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Background: Hidradenitis suppurativa (HS) is a long-term skin disorder associated with high levels of psychological distress and significant life impact. Objective: To evaluate the quality of life, depression, anxiety, loneliness, and self-esteem in patients with HS. Methods: Ninety-four patients with HS were enrolled in the study. The quality of life, depression, anxiety, loneliness, and self-esteem of the patients were assessed using the Dermatology Life Quality Index (DLQI), the Hospital Anxiety and Depression Scale (HADS), the UCLA Loneliness Scale (UCLA-Version 3), and the Rosenberg Self-Esteem Scale (RSES), respectively. Results: The DLQI mean score was 11.43 ± 6.61 in patients with HS. The patients with HS presented statistically significantly higher anxiety (6.41 ± 3.31 vs. 5.00 ± 1.59, p < 0.001), depression (5.45 ± 2.79 vs. 4.16 ± 1.54, p < 0.001), and loneliness and social isolation scores (42.86 ± 8.63 vs. 35.57 ± 6.17, p < 0.001) and lower self-esteem scores (18.91 ± 1.79 vs. 19.77 ± 2.53, p = 0.008) than the healthy controls. Conclusions: HS is a distressing, recurrent disease that impairs quality of life. We can suggest services that allow an integrated approach, which includes psychosocial support, offering the patients relief from isolation and an opportunity to share common experiences.

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“…HS influences patients' lives in many ways [15] . HS patients experience several emotional reactions, including anger, sadness, anxiety, and depression.…”

Section: Discussionmentioning

confidence: 99%

Quality of Life and Psychosocial Implications in Patients with Hidradenitis Suppurativa

et al. 2016

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“…Several studies have previously demonstrated a significant reduction in quality of life (QoL), using Dermatology Life Quality Index (DLQI), among patients with HS (5,6). In fact, a study found that the mean DLQI scores for patients with HS (8.9) were higher than previously reported for other skin diseases, such as alopecia (8.3), acne (7.5) and psoriasis (7.0) (6).…”

Section: Short Communicationmentioning

confidence: 93%

Pain in Hidradenitis Suppurativa: A Pilot Study

Ring¹,

Sørensen²,

Miller³

et al. 2016

Acta Derm Venerol

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“…In a survey of patients receiving oral GC therapy for 60 days or more, 60 % of participants reported skin changes that were bothersome [ 13 ]. Skin changes can have substantial psychological effects and therefore affect patients' HRQoL [ 14 ]. Current EULAR recommendations do not advocate routine monitoring of skin thinning for low-dose oral GCs taken for less than 6 months [ 2 , 15 ].…”

Section: Nature and Pathophysiology Of Glucocorticoid Toxicities Skinmentioning

confidence: 99%

The Prediction and Monitoring of Toxicity Associated with Long-Term Systemic Glucocorticoid Therapy

et al. 2015

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Glucocorticoids are often required for adequate control of inflammation in many serious inflammatory diseases; common indications for long-term treatment include polymyalgia rheumatica, giant cell arteritis, asthma and chronic obstructive pulmonary disease. Long-term glucocorticoid therapy is, however, associated with many adverse effects involving skin, gastrointestinal, eye, skeletal muscle, bone, adrenal, cardio-metabolic and neuropsychiatric systems. This balance between benefits and risks of glucocorticoids is important for clinical practice and glucocorticoid-related adverse effects can significantly impair health-related quality of life. Understanding the nature and mechanisms of glucocorticoid-related adverse effects may inform how patients are monitored for toxicity and identify those groups, such as older people, that may need closer monitoring. For clinical trials in diseases commonly treated with glucocorticoids, standardised measurement of glucocorticoid-related adverse effects would facilitate future evidence synthesis and meta-analysis.

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Self-Reported Skin Morbidities and Health-Related Quality of Life: A Population-Based Nested Case-Control Study

Cited by 46 publications

References 41 publications

Quality of Life and Psychosocial Implications in Patients with Hidradenitis Suppurativa

Quality of Life and Psychosocial Implications in Patients with Hidradenitis Suppurativa

Pain in Hidradenitis Suppurativa: A Pilot Study

The Prediction and Monitoring of Toxicity Associated with Long-Term Systemic Glucocorticoid Therapy

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