Self‐Reported Weight‐Loss Methods and Weight Change: Ten‐Year Analysis in the Swedish Obese Subjects Study Control Group

Zenténius, Edit; Andersson‐Assarsson, Johanna C.; Carlsson, Lena; Svensson, Per‐Arne; Larsson, Ingrid

doi:10.1002/oby.22200

Cited by 24 publications

(16 citation statements)

References 31 publications

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“…This is particularly important because of the high prevalence of previous weight loss attempts among persons with obesity, the lack of standardized weight control methods offered by the health care system, and the discouraging long-term results of weight loss attempts. 23,24,28 In the current study, it was not specified whether the support required for weight loss meant support from the health care provider or, for example, from family, friends or others, but because of the high prevalence of various types of health problems, it seems reasonable that the support should be provided by the health care system. Multiple barriers to weight loss, such as high BMI, more health conditions, and low confidence among patients with obesity, have also been reported from a study conducted in primary care in the United Kingdom.…”

Section: Discussionmentioning

confidence: 98%

“…However, an English study found that weight loss attempts were only modestly related to health conditions . Although trying to lose weight is very common among people with obesity, the long‐term results are discouraging . More knowledge is thus needed about the health status, contacts with health care, and other health‐related factors among those who want to lose weight and do not/do need weight loss support.…”

Section: Introductionmentioning

confidence: 99%

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Desire to lose weight and need of weight loss support in the adult population—Results from a cross‐sectional study in Sweden

Molarius

Lindén-Boström

Karlsson

2020

Obesity Science & Practice

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Summary Objective Evidence‐based methods to lose weight are important in tackling increasing obesity trends in adult populations. More knowledge about persons who want to lose weight and do not/do need weight loss support is necessary to design effective preventive practices. Thus, the aim of the study was to investigate the prevalence of desire to lose weight in the general population and the prevalence of health problems and health‐related factors in persons with overweight or obesity who want to lose weight and believe that they do not/do need weight loss support. Methods The study included 14 126 persons aged 30 to 69 years who responded to a questionnaire sent to a random sample. Persons with overweight or obesity (BMI ≥ 25 kg/m2) were divided into three groups: those who do not want to lose weight (n = 1236), those who want to lose weight but do not believe they need support (n = 5484), and those who want to lose weight and believe they need weight loss support (n = 1462). Results In total, 69% of the women and 59% of the men reported that they wanted to lose weight. The prevalence of hypertension, musculoskeletal pain, poor self‐rated health, anxiety/worry, and depression was highest among persons with overweight or obesity who wanted to lose weight and believed they need weight loss support. They were also more physically inactive and reported less social support. Conclusions To want to lose weight is very common among adults. People with overweight or obesity who want to lose weight and believe they need weight loss support have higher frequency of various health problems, including mental health problems, and less social support.

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Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Desire to lose weight and need of weight loss support in the adult population—Results from a cross‐sectional study in Sweden

Molarius

Lindén-Boström

Karlsson

2020

Obesity Science & Practice

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“…Subjects from the surgery group underwent bariatric surgery at baseline (19% gastric banding, 68% vertical banded gastroplasty and 13% gastric bypass). The control group received conventional non-surgical obesity treatment at their centres of registration (ranging from intensive lifestyle modifications to no treatment of any kind) and no attempt was made to standardize the non-surgical treatment [ 22 ]. All the subjects gave their written or oral informed consent to participate in the study.…”

Section: Methodsmentioning

confidence: 99%

Bariatric surgery and the incidence of rheumatoid arthritis – a Swedish Obese Subjects study

et al. 2019

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Objective The aim of this study was to determine the effect of bariatric surgery on the incidence of RA in participants of the Swedish Obese Subjects (SOS) study. Methods The SOS is a longitudinal study aiming to assess the effect of bariatric surgery on mortality and obesity-related diseases. This report includes 2002 subjects with obesity who underwent bariatric surgery and 2034 matched controls; none of them had RA at baseline. Cases of incident RA were identified through the Swedish National Patient Register by searching for International Classification of Diseases codes. Both intention-to-treat analyses and per-protocol analyses are reported. In the per-protocol analysis, participants from the control group who underwent bariatric surgery later on during follow-up were censored at the time of surgery. Results During follow-up, 92 study participants developed RA. The median follow-up was 21 years (range 0–29). Bariatric surgery was neither associated with the incidence of RA in the intention-to-treat analysis [hazard ratio (HR) 0.92 (95% CI 0.59, 1.46), P = 0.74], nor in the per-protocol analysis [HR 0.86 (95% CI 0.54, 1.38), P = 0.53]. Weight change at the 2 year follow-up, expressed as the change in BMI compared with baseline, did not associate with the development of RA. Higher serum CRP levels and smoking associated with the future development of RA independent of other factors. Conclusions We did not detect any association between bariatric surgery and the incidence of RA in subjects affected by obesity followed up for up to 29 years. ClinicalTrials.gov (http://clinicaltrials.gov): NCT01479452.

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“…Subjects from the bariatric surgery group underwent vertical banded gastroplasty (68%), gastric banding (19%), or gastric bypass (13%). The control group received conventional non-surgical treatment for obesity at their centres of registration, which ranged from intensive lifestyle modifications to no treatment, with no attempt to standardize the non-surgical treatment (31).…”

Section: Sos Study Designmentioning

confidence: 99%

Elevated adiponectin predicts the development of rheumatoid arthritis in subjects with obesity

Zhang

Peltonen

Andersson‐Assarsson

et al. 2020

Scandinavian Journal of Rheumatology

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Objective The aim of the current study is to determine whether baseline serum adiponectin levels predict the development of rheumatoid arthritis (RA). Method The current report includes 3693 individuals from the Swedish Obese Subjects (SOS) study. The original SOS study is a longitudinal non-randomized controlled study aiming to assess the effect of bariatric surgery on obesity-related mortality and morbidity. Participants included in the present report had adiponectin measurement available at baseline and no prevalent RA. The diagnosis of RA was retrieved through the Swedish National Patient Register. Results During a follow-up for up to 29 years, 82 study participants developed RA. Elevated baseline adiponectin levels were associated with a higher risk of developing RA independently of other factors, including C-reactive protein (CRP) and smoking [hazard ratio (HR) 1.70, 95% confidence interval (CI) 1.12-2.60 for an increase in adiponectin of 10 mg/L, p = 0.01]. After stratifying the population according to adiponectin and CRP median at baseline, study participants with both adiponectin and CRP above the median had a higher risk of developing RA compared to subjects with adiponectin and CRP below the median (HR 2.80, 95% CI 1.25-6.31, p = 0.01). Conclusions In this cohort of subjects with obesity followed up for up to 29 years, high serum adiponectin levels at baseline were associated with an increased risk for RA. Moreover, subjects with both high adiponectin and CRP levels at baseline were at particular risk of developing RA. ClinicalTrials.gov Identifier: NCT01479452. Adiponectin is a relatively abundant adipokine in plasma, with concentrations ranging from 2 to 30 mg/L and accounting for up to 0.05% of total plasma proteins (1, 2). Although mostly produced by the adipose tissue, adiponectin levels are inversely correlated with fat mass and are low in subjects with obesity (3, 4). Low serum adiponectin is associated with an unhealthy metabolic profile, including a higher risk for type 2 diabetes and insulin resistance (5-7). It has been hypothesized that the low adiponectin levels observed in obesity and its comorbidities are a consequence of the chronic low-grade inflammation that affects the adipose tissue under these circumstances (8, 9). However, other studies show that adiponectin levels are elevated in inflammatory and autoimmune diseases (10-12). Indeed, in patients with established rheumatoid arthritis (RA), adiponectin is increased in both serum and synovia, and subjects with early treatment-naïve RA have higher circulating adiponectin levels than controls. Moreover, plasma adiponectin is associated with pro-inflammatory cytokines in a population without RA but at high risk of developing the disease (13), suggesting that adiponectin may play a role in the early phases of disease development (14-17). This

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Self‐Reported Weight‐Loss Methods and Weight Change: Ten‐Year Analysis in the Swedish Obese Subjects Study Control Group

Cited by 24 publications

References 31 publications

Desire to lose weight and need of weight loss support in the adult population—Results from a cross‐sectional study in Sweden

Desire to lose weight and need of weight loss support in the adult population—Results from a cross‐sectional study in Sweden

Bariatric surgery and the incidence of rheumatoid arthritis – a Swedish Obese Subjects study

Elevated adiponectin predicts the development of rheumatoid arthritis in subjects with obesity

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