Self reports of post-vaccination outcome by COVID-19 vaccine recipients across various study settings

Abstract

Background India rolled out its vaccination program against COVID 19 on and from 16th January 2021. Apart from preventive measures like Covid Appropriate Behavior, vaccines were introduced as key specific protection against the virus in several parts of world. The present study is designed to profile spectrum of post vaccination outcome in terms of clinical signs/symptoms including adverse effects encountered among recipients across India. Methods: An online cross-sectional survey was conducted among 188 vaccine recipients of more than 18 years of age through snow ball sampling using a semi- structured, pre tested instrument with appropriate questions after taking informed consent. Results: In this study 12.7 % were found to have tested positive for COVID-19 and 28.7 %were having various co-morbidity. Among all co-morbidities hypertension, diabetes and obesity were statistically significant with Covid status of the patients. ‘Pain at injection site’ was the most common symptom observed among Covid-19 positive and negative groups. A significant difference was observed between proportions of recipients with ‘fever’, ‘chills’ and ‘fatigue’ implying an association between test status for Covid and the symptoms. Within first 24 hours, 38.5% people had experienced ‘arthralgia’ and 71% of the people had reported ‘pain at injection site’.