Self-treatment and adverse reactions with herbal products for treating symptoms associated with anxiety and depression in adults from the central-western region of Mexico during the Covid-19 pandemic

Alonso-Castro, Ángel Josabad; Ruiz-Padilla, Alan Joel; Ortiz-Cortes, Miriam; Carranza, Eleazar; Ramírez‐Morales, Marco Antonio; Escutia-Gutiérrez, Raymundo; Ruiz‐Noa, Yeniley; Zapata-Morales, Juan Ramón

doi:10.1016/j.jep.2021.113952

Cited by 22 publications

(22 citation statements)

References 37 publications

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“…A similar result found that one of the Chinese herbs used to treat COVID-19 had drug interaction through inhibiting CYP3 and prolonging t1/2 lopinavir [41]. In addition, ginger, honey, and lemon were herbs frequently used in COVID-19 and several cases related to those herb-drug interactions were documented [18,[42][43][44]. Therefore, patients need to provide information to healthcare professionals on the traditional medicines consumed when using medicine to avoid unintended interaction, and both patients and healthcare professionals should be aware of potential interaction between herbs and drugs prescribed [18,45,46].…”

Section: Fig 2 the Percentage Using A Combination Therapy Of Herbs An...mentioning

confidence: 71%

Factors Affecting the Uptake of Combination Therapy for the Treatment of COVID-19

Restinia

Musir

Aldrat

et al. 2022

JPRI

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Aims: To analyze factors affecting the use of a combination of herbs and medication or supplements for COVID-19 treatment among self-isolation patients. Methodology: A cross-sectional study was conducted to 268 COVID-19 patients with home self-isolation in Indonesia. Data were collected by using a google form questionnaire, consisting of closed-formatted and open-ended questions, from October 9th to December 9th, 2021. A multivariate analysis was performed using a logistic regression test. Results: The proportion of COVID-19 patients who used a combination of herbs and medication or supplements was 78.4%. Vitamin C, vitamin D, and paracetamol were the medication and supplements most frequently taken by patients. The most commonly consumed herbs were honey (70.7%), ginger (50.18%), and saffron (26.74%). The multivariate analysis results showed that the duration of infection, sunbathing activities, and marital status were factors significantly associated with the use of a combination of herbs and medication or supplements (P<0.05). Conclusion: This study highlighted that most COVID-19 patients used herbs in combination with medication or supplements for their treatment. Therefore, there is a necessity for education, especially for patients and health professionals about the potential herb-drug interactions.

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Section: Fig 2 the Percentage Using A Combination Therapy Of Herbs An...mentioning

confidence: 71%

Factors Affecting the Uptake of Combination Therapy for the Treatment of COVID-19

Restinia

Musir

Aldrat

et al. 2022

JPRI

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“…Among the population-based survey studies, thirty-one were conducted through online surveys only ( 17 , 18 , 20 , 22 , 23 , 25 , 26 , 28 – 31 , 35 , 42 , 43 , 45 , 48 – 54 , 57 – 62 , 66 , 68 , 74 ), one was an in-person interview ( 56 ), three were telephone interviews ( 10 , 21 , 38 ), and two were both in-person and online surveys ( 19 , 36 ). Among the included studies, usage status of the interventions, including TCM ( n = 22) ( 27 , 32 – 34 , 37 , 39 , 40 , 44 , 47 , 55 , 63 – 65 , 67 , 69 – 73 , 75 – 77 ), functional food (supplements) or herbs ( n = 20) ( 17 – 24 , 29 , 36 , 38 , 43 , 49 – 52 , 57 – 59 ), mind-body practice or spiritual practice ( n = 9) ( 28 , 35 , 42 , 45 , 48 , 54 , 60 , 61 , 74 ), Ayurveda ( n = 2) ( 10 , 41 ), homeopathy ( n = 1) ( ...…”

Section: Resultsmentioning

confidence: 99%

“…Most of the data for surveys or patient chart reviews were collected during 2020. In approximately half of the studies, TCIM interventions were used for prophylactic purposes ( n = 28) ( 17 – 20 , 22 , 23 , 25 , 26 , 28 , 31 , 35 , 36 , 38 , 41 , 42 , 45 , 48 – 54 , 59 , 61 , 62 , 66 , 74 ), and the other half were used for therapeutic purposes ( n = 27) ( 21 , 24 , 27 , 32 – 34 , 37 , 39 , 40 , 44 , 46 , 47 , 55 , 58 , 63 – 65 , 67 , 69 – 73 , 75 – 77 ) ( Table 1 ).…”

Section: Resultsmentioning

confidence: 99%

Use of Traditional, Complementary and Integrative Medicine During the COVID-19 Pandemic: A Systematic Review and Meta-Analysis

et al. 2022

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BackgroundTraditional, Complementary and Integrative Medicine (TCIM) has been reported to use for symptom management of coronavirus disease 2019 (COVID-19). The objective of this review was to identify the overall usage prevalence of TCIM interventions for COVID-19.MethodsSurveys on the general population and observational studies on the COVID-19 patient chart review were located in the search of PubMed, EMBASE and Cochrane Central Register of Controlled Trials databases in September 2021. Observational studies, such as cross-sectional studies, surveys, cohort studies and hospital-based patient case reviews, published in any language, reporting the usage of TCIM in the patients with COVID-19 or the general population during the COVID-19 pandemic were included in this review. Data screening and extraction were performed independently by two reviewers. The reporting quality of the included studies was assessed with the STrengthening the Reporting of OBservational studies in Epidemiology (STROBE) statement. To conduct a meta-analysis of the usage prevalence of various TCIM interventions, the effect size of the proportion for each intervention was calculated with the inverse variance method. The main outcome was usage prevalence of TCIM interventions among patients with COVID-19 or the general population during the COVID-19 pandemic.ResultsA total of 62 studies were included in this review. The overall TCIM usage prevalence was estimated to be 0.64 (95% CI 0.54–0.73). The overall prevalence did not differ between the population-based survey (0.65, 95% CI 0.48–0.81) and the hospital-based patient case review (0.63, 95% CI 0.52–0.73). Statistical heterogeneity and comparatively low quality in reporting were observed, which should be cautiously considered when interpreting the results.ConclusionVarious TCIM interventions were reported to be used with comparatively high frequency. Future international collaborative research might overcome the main limitation of this study, i.e., the heterogeneity of the included data.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?RecordID=278452, identifier: CRD42021278452.

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“…Personal factors, such as previous personal experiences, absence of health insurance, having children, having adequate knowledge, and the need to pursue a livelihood, were found to affect the use of natural products during a disease outbreak (Ismail & Al Hashel, 2021;Alonso-Castro et al, 2021;Thebe, 2022;Nguyen et al, 2021;Hughes et al, 2012). These were found to interrelate with other factors which in uence people's perceptions of the e cacy and safety of natural products and their ability to access and afford them.…”

Section: Personal Factorsmentioning

confidence: 98%

Critical Assessment of the Implications of Self-medication With Natural Products During Disease Outbreaks Among People in Developing Countries

Adebiyi¹

2023

Preprint

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Background: Self-medication with natural products during disease outbreaks is a major public health challenge in developing countries. Unlike self-medication with Over the counter (OTC) medication which receives significant attention in published literature, natural products have significant health implications, especially during times of disease outbreaks which are yet to be fully explored. Not backed by scientific evidence, the act can lead to a false sense of security among people, leading to a further spread of the disease amongst other implications. People need to be informed about self-medication risks and the professionally prescribed benefits of natural products and to seek appropriate medical care when necessary. Objectives: The purpose of this dissertation is to assess the implications of self-medication with natural products during disease outbreaks among people in developing countries. It tries to answer the following questions: (1) what is the state and quality of evidence in current literature (2) what are the gaps in literature (3) what are the determinants and contributing factors to self-medication with natural products during disease outbreaks among people in developing countries (4) what are the implications and (5) what are the possible solutions? Method: This dissertation was conducted using a modified systematic literature review methodology. The search protocol utilised for the search and selection of relevant materials from literature used in synthesising the findings of the study was documented using the PRISMA. The database search result was selected for review after the application of limiters, duplicate removals, exclusion and inclusion criteria, full-text review, and screening. The final selected articles were assessed for quality and bias using the 20 points system in AXIS critical evaluation tool. Data were extracted into themes using a Microsoft word table from which findings were synthesised. Findings: The initial database search yielded 1,683 reports from which 20 articles were selected for the review. Overall, 71.4% of the 14 articles assessed for quality and bias accrued 15 or more points on the 20 points system in AXIS critical evaluation tool, indicating that they were relatively of good quality. While all twenty (20) articles mentioned at least three or more factors or determinants of self-medication with natural products during disease outbreaks, only six (6) articles mentioned one or more implications, therefore demonstrating that there is a dearth in literature in this regard, which needs more exploration. The findings indicate that women are more likely to self-medicate with natural products than men, acquisition and ideological factors had the most influence on self-medication while the most common side effects were Diarrhoea, Stomach pain, Sweating, Headache, and Nausea/vomiting. Findings indicate that steam inhalation and herbal baths increased the risk of COVID-19 infection and people who self-medicate with natural products are more withdrawn and had less communication with their physicians. These people may suffer side effects not reported to their doctor and this might account for the paucity of reports on the implications of natural products used during disease outbreaks. Conclusion and implication of key finding:The use of natural products for self-medication during disease outbreak is a rampant practice in developing countries. While natural products may be more readily available, accessible, and affordable, there are potential risks and implications of natural products' use for self-medication. People need to be informed about this, encouraged to speak about their predicaments and seek appropriate medical care and support when necessary.

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Self-treatment and adverse reactions with herbal products for treating symptoms associated with anxiety and depression in adults from the central-western region of Mexico during the Covid-19 pandemic

Cited by 22 publications

References 37 publications

Factors Affecting the Uptake of Combination Therapy for the Treatment of COVID-19

Factors Affecting the Uptake of Combination Therapy for the Treatment of COVID-19

Use of Traditional, Complementary and Integrative Medicine During the COVID-19 Pandemic: A Systematic Review and Meta-Analysis

Critical Assessment of the Implications of Self-medication With Natural Products During Disease Outbreaks Among People in Developing Countries

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