SEM observation of cultured, mitogen-stimulated leukocytes. Cells obtained from patients with acute myeloblastic and chronic lymphocytic leukemias

Abstract

SEM observation of acute myeloblastic leukemia cells, incubated for 20 h with the mitogens pokeweed and phytohaemagglutinin, showed these to have elongated structures that were either smooth or partially covered by thumblike figures. By contrast, the chronic lymphocytic leukemia cells possessed more compact shapes and some were covered with blebs of varying sizes.