2019
DOI: 10.21315/mjms2019.26.1.6
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SEMA3B but Not CUL1 as Marker for Pre-Eclampsia Progression

Abstract: BackgroundAn imbalance between pro- and anti-angiogenic factors contributes to impaired trophoblast invasion during pregnancy, leading to failure of uterine spiral artery remodeling, blood vessel ischemia, and pre-eclampsia (PE). Anti-angiogenic semaphorin 3B (SEMA3B) and pro-angiogenic cullin 1 (CUL1) are expressed in both the placenta and maternal blood. The present study investigated correlations between serum and placental SEMA3B as well as CUL1 levels in late-onset PE.MethodsThis cross-sectional study inc… Show more

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Cited by 7 publications
(2 citation statements)
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“…36 SEMA3B, the sense-cognate gene for SEMA3B-AS1, belongs to the SEMAs and is involved in different biological processes, such as apoptosis, cell invasion, cell migration, and angiogenesis. 37 In our study, we found that the RNA levels of SEMA3B-AS1 and SEMA3B in CRC were significantly correlated. Notably, a change in SEMA3B-AS1 abundance through overexpression and knockdown particularly affected SEMA3B mRNA and protein expression.…”
Section: F I G U R E 5 Sema3b-as1 Requires Ep300/sema3b To Suppress C...supporting
confidence: 52%
See 1 more Smart Citation
“…36 SEMA3B, the sense-cognate gene for SEMA3B-AS1, belongs to the SEMAs and is involved in different biological processes, such as apoptosis, cell invasion, cell migration, and angiogenesis. 37 In our study, we found that the RNA levels of SEMA3B-AS1 and SEMA3B in CRC were significantly correlated. Notably, a change in SEMA3B-AS1 abundance through overexpression and knockdown particularly affected SEMA3B mRNA and protein expression.…”
Section: F I G U R E 5 Sema3b-as1 Requires Ep300/sema3b To Suppress C...supporting
confidence: 52%
“…ZEB1‐AS1 activated the expression of ZEB1 in prostate cancer 36 . SEMA3B, the sense‐cognate gene for SEMA3B‐AS1 , belongs to the SEMAs and is involved in different biological processes, such as apoptosis, cell invasion, cell migration, and angiogenesis 37 . In our study, we found that the RNA levels of SEMA3B‐AS1 and SEMA3B in CRC were significantly correlated.…”
Section: Discussionmentioning
confidence: 48%