2021
DOI: 10.1186/s12911-021-01487-w
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Semantic categorization of Chinese eligibility criteria in clinical trials using machine learning methods

Abstract: Background Semantic categorization analysis of clinical trials eligibility criteria based on natural language processing technology is crucial for the task of optimizing clinical trials design and building automated patient recruitment system. However, most of related researches focused on English eligibility criteria, and to the best of our knowledge, there are no researches studied the Chinese eligibility criteria. Thus in this study, we aimed to explore the semantic categories of Chinese eli… Show more

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Cited by 18 publications
(7 citation statements)
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“…ERNIE with the splitting ratio of 8: Transformer is built entirely on a self-attentive mechanism, which not only allows parallel operations but also captures long-range feature dependencies [20]. In the classi cation task of Chinese eligibility criteria sentences, ERNIE narrowly beat BERT's results in both micro and macro F 1 score [21], and it exhibited higher accuracy under the same conditions which was consistent with the results of this study. The results of the nal hidden layer computation we can perform downstream tasks by changing the pretrained model parameters which is also called ne-tuning.…”
Section: Discussionsupporting
confidence: 83%
“…ERNIE with the splitting ratio of 8: Transformer is built entirely on a self-attentive mechanism, which not only allows parallel operations but also captures long-range feature dependencies [20]. In the classi cation task of Chinese eligibility criteria sentences, ERNIE narrowly beat BERT's results in both micro and macro F 1 score [21], and it exhibited higher accuracy under the same conditions which was consistent with the results of this study. The results of the nal hidden layer computation we can perform downstream tasks by changing the pretrained model parameters which is also called ne-tuning.…”
Section: Discussionsupporting
confidence: 83%
“…The ERNIE model is more capable of capturing and grasping semantic information. It had shown superior performance over BERT in previous Chinese corpus learning studies [ 25 , 29 ].…”
Section: Methodsmentioning
confidence: 99%
“…These ERNIEs have few differences and they all perform well in the tasks with specific Chinese-language medical environments. In the classification task of Chinese eligibility criteria sentences, ERNIE outperformed baseline machine learning algorithms and deep learning algorithms [ 25 ].…”
Section: Methodsmentioning
confidence: 99%
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“…The second one is an application category classification dataset (IFLYTEK) maintained by CLUE . The third one is a clinical trial criterion categorization dataset (CTC) (Zong et al, 2021). The fourth one is an entity typing dataset (MSRA) originally released as a named entity recognition dataset (Levow, 2006).…”
Section: Setupmentioning
confidence: 99%