Disagreement exists regarding the functional locus of semantic interference of distractor words in picture naming. This effect is a cornerstone of modern psycholinguistic models of word production, which assume that it arises in lexical response-selection. However, recent evidence from studies of dual-task performance suggests a locus in perceptual or conceptual processing, prior to lexical response-selection. In these studies, participants manually responded to a tone and named a picture while ignoring a written distractor word. The stimulus onset asynchrony (SOA) between tone and picture-word stimulus was manipulated. Semantic interference in naming latencies was present at long tone pre-exposure SOAs, but reduced or absent at short SOAs. Under the prevailing structural or strategic response-selection bottleneck and central capacity sharing models of dual-task performance, the underadditivity of the effects of SOA and stimulus type suggests that semantic interference emerges before lexical response-selection. However, in more recent studies, additive effects of SOA and stimulus type were obtained. Here, we examined the discrepancy in results between these studies in 6 experiments in which we systematically manipulated various dimensions on which these earlier studies differed, including tasks, materials, stimulus types, and SOAs. In all our experiments, additive effects of SOA and stimulus type on naming latencies were obtained. These results strongly suggest that the semantic interference effect arises after perceptual and conceptual processing, during lexical response-selection or later. We discuss several theoretical alternatives with respect to their potential to account for the discrepancy between the present results and other studies showing underadditivity. Keywords: dual-task performance, picture-word interference, response-selection bottleneck, semantic interference, Stroop An important question in the psychology of language concerns how speakers select from memory the words that they want to produce. This ability, called lexical selection, is a topic of much research in the field of word production. One way of studying lexical selection consists of presenting participants with pictured objects paired with superimposed distractor words, a paradigm called picture-word interference (PWI; see Abdel Rahman & Melinger, 2009;Glaser, 1992;Roelofs, 2007, for reviews). Participants are instructed to name the pictures and to ignore the distractors. The relation the distractor word bears with the picture name (e.g., semantic, phonological, etc.) is manipulated and effects obtained are thought to inform researchers about processes involved in word production.One specific effect has long been assumed to provide evidence about the nature of lexical selection: semantic interference (e.g., Damian & Martin, 1999;Levelt, Roelofs, & Meyer, 1999;Roelofs, 1992;Schriefers, Meyer, & Levelt, 1990;Starreveld & La Heij, 1996). This effect concerns the finding that response times (RTs) are longer for picture naming when the dis...