Manuscript (TeX or Word only) Click here to access/download;Manuscript (TeX or Word only);Manuscript.tex JASA/Sample JASA Article The assessment of intracortical bone properties is of interest since early-stage osteoporosis is associated with resorption in the endosteal region. However, understanding the interaction between ultrasonic guided waves and the cortical bone structure remains challenging. The purpose of this work is to investigate the effect of intracortical bone properties on the ultrasonic response obtained at low-frequency (<100 kHz) using an axial transmission configuration. The semi-analytical finite element method was used to simulate the propagation of guided waves in a waveguide with realistic geometry and material properties. An array of 20 receivers was used to calculate the phase velocity and cutoff frequency of the excited modes using the 2D Fourier transform. The results show that the position of the emitter around the circumference of the bone is an important parameter to control since it can lead to variations of up to 10 dB in the amplitude of the transmitted modes. The cutoff frequency of the high order modes was, however, only slightly affected by the circunferential position of the emitter, and was sensitive mainly to the axial shear modulus. The phase velocity and cutoff frequency in the 20-85 kHz range are promising parameters for the assessment of intracortical properties.