“…Intraosseous access can be considered clinically appropriate on the basis of a shortterm need for patients • with chronic disease who have been admitted to the hospital for treatment of a medical event, for example, the deteriorating patient with chronic obstructive pulmonary disease; • with limited vascular access due to aggressive treatment modalities, for example, fistulas, grafts, shunts, mastectomies, or multiple central catheter placements; • for whom Rapid Response Teams are called to prevent an emergent situation and in whom obtaining peripheral or central IV access is difficult; • who experience an unexpected medical event that causes their peripheral or central IV device to become nonfunctional, for example, infiltration or occlusion, and difficult to reestablish; • who have limited peripheral access due to morbid obesity; • who suffer from intractable pain; • who are in the early stages of sepsis; • who are receiving palliative or hospice care; • who are undergoing anesthesia and experience prolonged, difficult, or failed IV access. 26,27 …”