“…To deal with this problem, many of the methods proposed in the literature have used semi-automatic segmentation (Rabben et al, 2000;Mahdavi et al, 2011;Duarte et al, 2013;Ni et al, 2015), in which a human localizes a suitable region, and then segmentation algorithms delineate the selected region. This study was designed to automatically detect ROIs and delineate their boundaries.…”