Seminal vesicle carcinoma

Oxley, Jon; Brett, Mary; Gillatt, David; Burton, P.

doi:10.1111/j.1365-2559.1999.0696g.x

Cited by 24 publications

(22 citation statements)

References 6 publications

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“…1,3,11,18 This is an excellent marker of well-differentiated adenocarcinoma of the seminal vescicles. 18 Carcinoembryonic antigen has been positive in most cases, 1,6,16,19 but exceptional reports, including ours, have been negative. 1,3 No guidelines for the management of these cases have been clearly defined.…”

Section: Discussionmentioning

confidence: 63%

Primary Bilateral Seminal Vesicle Carcinoma

et al. 2012

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With no more than 60 reported cases, tumors of the seminal vesicles are rare. Because of poor and nonspecific symptoms diagnosis is often very difficult. This report presents a case of a 56-year-old man with right renal agenesis and intermittent hematospermia and bilateral cystic masses of the seminal vesicles. Transrectal biopsies of the cystic lesion revealed a papillary clear cell adenocarcinoma. The patient underwent radical prostatectomy and pelvic lymphoadenectomy. Lymph node metastases were found on histological examination. The patient received 4 cycles of chemotherapy and pelvic radiotherapy. He remains disease free 21 months after surgery. Radiological imaging in patients with hematospermia and hematuria will allow disease detection at earlier stages. Immunohistochemistry and histomorphology can be used for differential diagnosis. Surgery with clear margins offers the best chance to cure. Hormonal and radio-chemotherapy have a role as adjuvant and palliative treatment.

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Section: Discussionmentioning

confidence: 63%

Primary Bilateral Seminal Vesicle Carcinoma

et al. 2012

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“…Among the most common presenting symptoms are hematuria and hematospermia, but urinary infection, dysuria, painful defecation and pelvic pain have also been reported. [3] These symptoms are not cancer-specific and when they occur as the presenting symptoms of cancer, other malignancies are far more common than SVC. Actually, our patient had no similar symptoms and thus the diagnosis was further delayed.…”

Section: Discussionmentioning

confidence: 99%

“…The accepted criteria include no other demonstrable tumor and either an anaplastic or papillary histological appearance. [3] In several cases however, some mucinous differentiation is present. [9] Desmoplasia may also be observed around infiltrating glands.…”

Section: Discussionmentioning

confidence: 99%

“…[11] CK7 staining may be strongly positive, whereas CK20 staining is usually negative. [3] This keratin profile might be helpful in the differential diagnosis of adenocarcinomas whose primary site is the prostate gland (these are usually CK7 negative and CK 20 positive). Similar to ASV, urinary bladder adenocarcinomas are usually CK7 positive and CK 20 negative and thus must be distinguished from SVC based on the topography, morphology and lack of CA125 expression.…”

Section: Discussionmentioning

confidence: 99%

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Primary adenocarcinoma of the seminal vesicles: a phantom tumor

Tyritzis¹,

Stamatiou²,

Zizi-Sermpetzoglou³

et al. 2012

Turkish Journal of Urology

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Primary adenocarcinoma of the seminal vesicles (ASV) is a very rare neoplasm with less than 50 histologically confirmed cases reported in the literature. The diagnosis is complex and is based on a combination of immunohistochemical, clinical and radiological findings. Biopsy is not always conclusive, and surgical resection is usually required to determine whether the tumor originated from the seminal vesicles. We present a case of primary ASV that was discovered upon investigation of inguinal lymphadenopathy. A history of recent hormonal manipulation for the treatment of infertility may be associated with the development or the progression of this rare tumor.

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“…En ocasiones fue necesario plantear también cistectomía 7 . La radioterapia parece haber sido indicada con carácter paliativo en casos excesivamente avanzados de muy mal pronóstico 8 . Otros autores han llevado a cabo tratamiento adyuvante con antiandrógenos o Figura 1 Quiste retrovesical con crecimiento exofítico parietal en RM.…”

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