Seminoma with Hyperesterogenemia in a Yorkshire Terrier

Abstract

ABSTRACT. A male 8-year-old Yorkshire Terrier dog with unilateral cryptorchism was presented for investigation of reduced appetite and multifocal alopecia. Abdominal sonography and radiography demonstrated abnormal enlargement of left testicle in abdominal cavity. Both of the retroperitoneal cryptorchid testicle and the other contralateral testicle were removed surgically. The concentrations of testosterone and estradiol in blood collected from the jugular vein and the two spermatic veins were evaluated and the results revealed high estradiol concentration. The retroperitoneal cryptorchid testicle was enlarged, firm, bulging sphere mass. The cut surface revealed homogeneous white color and lobulation by septa. The contralateral testicle in scrotum showed atrophic testicle and enlarged epididymis. Histopathologically, the retroperitoneal cryptorchid testicle was diagnosed as seminoma. We thought that hyperesterogenemia and alopecia in this case was probably related with his seminoma, although high correlations between Sertoli cell tumor and alopecia have been reported. To our knowledge, this report may be a rare case of seminoma with hyperesterogenemia and alopecia.

Bilaterally diffuse malignant seminoma in a dog

“…Seminomas are usually documented in right testicle and can be found in solitary or multiple masses. They generally had pulpy consistency (4,9,10). Cut sections can be coincided with haemorragie and necrosis.…”

“…Seminomas, sertoli cell tumors and Leydig cell tumors are most encountered among primary testicle tumors according to World Health Organization (WHO) (1,4,6,7,9). And histologically evaluated mainly in two types (tubular and diffuse type).…”

“…Testicle tumors give rise to feminism, gynecomasti and growing in testicles. Moreover, the tumors can cause to prostatic and haematologic disorders, skin diseases and also perianal tumors (4,6,8,11). In the case, general constitution and condition of the dog are well informed in anamnesis.…”

Hyperoestrogenism and mammary adenosis associated with a metastatic Sertoli cell tumour in a male Pekingese dog

“…It has been reported that the measurement of excessive intralesional oestradiol concentration can assist with the confirmation of the SCT metastasis (Gopinath et al 2009). Although SCTs are the most common testicular neoplasia to cause hyperoestrogenaemia, others have been reported, including a case of seminoma in a Yorkshire terrier (Kim and Kim 2005).…”

Bir köpekte malign seminom

“…Bu tümöre ayrıca aygır (9), koç, teke ve boğalar ile diğer türlerde de az oranda rastlanır (4). Kriptorşidizm seminom oluşu-munda predispoze bir faktördür.…”