Senegalin, a new phenylpropanoid and other secondary metabolites from the stem bark of Ekebergia senegalensis A. Juss. (Meliaceae)

Pharmacognostical studies and phytochemical evaluation of four Meliaceae plants widely use in ethnomedicine across West Africa

“…From a phytochemical point of view, the Meliaceae family has an abundant and highly diversified chemical profile, characterized by the presence of phenolic and terpene compounds [5] . The leaves of E. senegalensis [12] and P. kotschyi contain flavonoids [9,11] , saponosides and steroids. The trunk bark and leaves of T. emetica contain polyphenols, flavonoids, tannins, saponosides and terpenoids [12,14] .…”

“…The leaves of E. senegalensis [12] and P. kotschyi contain flavonoids [9,11] , saponosides and steroids. The trunk bark and leaves of T. emetica contain polyphenols, flavonoids, tannins, saponosides and terpenoids [12,14] . Furthermore, data from the scientific literature indicate a correlation between anti-inflammatory and analgesic activities [17] and the presence of phenolic and terpenic compounds in plant drugs.…”

Antimicrobial and cytotoxic extractives from <i>Ficus sycomorus</i> L. (Moraceae)

“…Infectious diseases commonly spread among humans are caused by the production of toxins by microbes in the human host also called dysbiosis of the human microbiota which will have a significant incidence on the immune system, leading to antibiotic resistance or causing the new emerging infectious or microbial diseases like HIV, hepatitis and many others (Brenchley & Douek, 2012;Cohen, 2016;Hand et al, 2012;Hu et al, 2016). Moreover, the resistance of infectious pathogens to existing drugs has been the major cause of the increasing rate of microbial diseases and the emergence of new ones around the world (Kemayou et al, 2021;Tabekoueng et al, 2020). The medicinal plants including those of the genus Ficus have been long used as the first line of treatment in folk medicine to manage several microbial illnesses and might represent a good source of new antimicrobial lead compounds to address the need for new potent drugs to face that resistance (Happi et al, 2021;Mbobda et al, 2021;Mbougnia et al, 2021).…”