“…Conventional robots offer advantages such as high operating speed, precise control, and ease of programming for intricate tasks. ,, However, these systems often lack adaptability in unstructured environments. ,, To mimic complete biological nervous systems, soft actuators have been introduced to emulate the functions of the motor and muscle systems. Soft actuators employ various responsive materials and mechanisms, including pneumatic, magnetic, thermal, or photoactuation, and electrical actuation. ,− Electrical actuation, in particular, has gained prominence due to its seamless integration into artificial systems. Ionic polymer–metal composite (IPMC) actuators, known as artificial muscles, operate under low voltages (<3 V) and offer advantages in integration compared to dielectric elastomer actuators (DEA), which require high kilovolt inputs. ,, However, IPMC actuators exhibit drawbacks such as slower response speeds and lower actuation strain (0.5–10%) compared to DEA (1–1000%). , Artificial systems have also explored biohybrid actuators, showcasing unique benefits such as self-healing, autonomous responses, and high energy efficiency. , These hybrid systems incorporate both nerve and muscle cells or tissues, and even organs including insect limbs or animal limbs. ,− This approach opens up possibilities for applications in biointerfaces, neuroprosthetics, and neurorehabilitation.…”