Sensitive analysis of aminoglycoside antibiotics via hyphenation of transient moving substitution boundary with field-enhanced sample injection in capillary electrophoresis

Ge, Shuping; Tang, Wanrong; Han, Ruobing; Zhu, Yan; Wang, Qingjiang; He, Pingang; Fang, Yuzhi

doi:10.1016/j.chroma.2013.04.049

Cited by 33 publications

(15 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The most used conventional methods for the detection of antibiotics are instrumental [5], such as capillary electrophoresis [6,7], gas chromatography [8,9] and liquid chromatography [9,10] coupled with mass spectrometry [11]. However, these methods are expensive and present limitations, such as the need for expensive laboratory instruments, time consuming separation/clean-up methodologies, long analysis time, extensive sample handling with multiple washing steps, use of expensive and polluting solvents and the impossibility to perform field analyses, making necessary the development of new sensors to overcome these limitations [12].…”

Section: Introductionmentioning

confidence: 99%

Magnetic Nanoparticles for Antibiotics Detection

2017

View full text Add to dashboard Cite

Widespread use of antibiotics has led to pollution of waterways, potentially creating resistance among freshwater bacterial communities. Microorganisms resistant to commonly prescribed antibiotics (superbug) have dramatically increased over the last decades. The presence of antibiotics in waters, in food and beverages in both their un-metabolized and metabolized forms are of interest for humans. This is due to daily exposure in small quantities, that, when accumulated, could lead to development of drug resistance to antibiotics, or multiply the risk of allergic reaction. Conventional analytical methods used to quantify antibiotics are relatively expensive and generally require long analysis time associated with the difficulties to perform field analyses. In this context, electrochemical and optical based sensing devices are of interest, offering great potentials for a broad range of analytical applications. This review will focus on the application of magnetic nanoparticles in the design of different analytical methods, mainly sensors, used for the detection of antibiotics in different matrices (human fluids, the environmental, food and beverages samples).

show abstract

Section: Introductionmentioning

confidence: 99%

Magnetic Nanoparticles for Antibiotics Detection

2017

View full text Add to dashboard Cite

show abstract

“…Instead of MSS or AFMC, Shuli et al described a transient moving substitution boundary method that has many parallels to these two approaches and thus has been included here. Their stacking system used crown ethers (18‐crown‐6‐tetracarboxylic acid (18C6H4)) as a pseudostationary phase to transport, release, and accumulate analytes at a substitution boundary.…”

Section: Stackingmentioning

confidence: 99%

“…Schematic illustration of the on‐line concentration with the FESI‐moving substitution boundary method: (A) starting situation of FESI with PSP plug and sample plug injected electrokinetically, (B) sample zone gets stacked under the electrical field, (C) focusing by moving substitution boundary principles, (D) CZE separation of the focused anlaytes. Reproduced from with permission.…”

Section: Stackingmentioning

confidence: 99%

Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2012–2014)

et al. 2015

View full text Add to dashboard Cite

One of the most cited limitations of capillary (and microchip) electrophoresis is the poor sensitivity. This review continues to update this series of biannual reviews, first published in Electrophoresis in 2007, on developments in the field of on-line/in-line concentration methods, covering the period July 2012-July 2014. It includes developments in the field of stacking, covering all methods from field-amplified sample stacking and large-volume sample stacking, through to ITP, dynamic pH junction, and sweeping. Attention is also given to on-line or in-line extraction methods that have been used for electrophoresis.

show abstract

“…Ge et al. reported a method combining FASI with 18‐crown‐6‐tetracarboxylic acid as a pseudostationary phase for the analysis of aminoglycoside antibiotics. Into a capillary filled with the BGE (15 mM Na 2 B 4 O 7 and 55 mM NaOH pH 12.5–12.9, in 0–30% ACN), a short pulse of the pseudostationary phase matrix (150 mM in the BGE) and then a long pulse of the sample (prepared with the pseudostationary phase at lower conductivity and pH 4.0) were introduced.…”

Section: Combined Stacking Techniquesmentioning

confidence: 99%

Contemporary sample stacking in analytical electrophoresis

et al. 2014

View full text Add to dashboard Cite

This contribution is a methodological review of the publications about the topic from the last 2 years. Therefore, it is primarily organized according to the methods and procedures used in surveyed papers and the origin and type of sample and specification of analytes form the secondary structure. The introductory part about navigation in the architecture of stacking brings a brief characterization of the various stacking methods, with the description of mutual links to each other and important differences among them. The main body of the article brings a survey of publications organized according to main principles of stacking and then according to the origin and type of the sample. Provided that the paper cited gave explicitly the relevant data, information about the BGE(s) used, procedure, detector employed, and reached LOD and/or concentration effect is given. The papers where the procedure used is a combination of diverse fragments and parts of various stacking techniques are mentioned in a special section on combined techniques. The concluding remarks in the final part of the review evaluate present state of art and the trends of sample stacking in CE.

show abstract

Sensitive analysis of aminoglycoside antibiotics via hyphenation of transient moving substitution boundary with field-enhanced sample injection in capillary electrophoresis

Cited by 33 publications

References 51 publications

Magnetic Nanoparticles for Antibiotics Detection

Magnetic Nanoparticles for Antibiotics Detection

Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2012–2014)

Contemporary sample stacking in analytical electrophoresis

Contact Info

Product

Resources

About