“…Recently, various designs of microplasma-based optical emission spectrometry (MP-OES) have been coupled with innovative sample introduction techniques and are widely used for the qualitative and quantitative analyses of biological molecules and metal ions in complex matrix samples. − Ultrasonic nebulization is characterized by uniform and fine droplet size, high nebulization efficiency, and low power consumption, which is an attractive sample introduction technique in the field of Li analysis using MP-OES. , Compared to pneumatic nebulization, ultrasonic nebulization generates a homogeneous aerosol with a smaller size, can nebulize solutions absorbed on solids such as filer paper, absorbent cotton swabs, and sponges, which is more suitable as a sample introduction method for DBS. Increased interest in ultrasonic nebulization MP-OES has studies typically focused on extending this technique for the detection of more elements, ,, with the result that its combination with DBS sample collection and introduction for the POCT of blood Li has never been realized.…”