Sensitive electrochemical determination of rifampicin using gold nanoparticles/poly-melamine nanocomposite

Amidi, Salimeh; Ardakani, Yalda Hosseinzadeh; Amiri-Aref, Mohaddeseh; Ranjbari, Elias; Sepehri, Zahra; Bagheri, Hasan

doi:10.1039/c7ra04865c

Cited by 53 publications

(28 citation statements)

References 34 publications

(34 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although these methods are generally quite sensitive and accurate, they are often costly, technically complex, time-consuming, and do not allow high throughput analysis. Recently, electrochemical methods, especially electrochemical RIF (rifampicin) sensors [10][11][12][13][14][15][16][17], have gained attention due to their outstanding merits, which includes the simplicity of the sample preparation, low cost of instrumentation, easy miniaturization, high sensitivity and selectivity. In particular, sensors based on metal oxide nanomaterials are well known for their excellent electrical, optical, thermal and catalytic properties, and large surface-to-volume ratio [18,19].…”

Section: Introductionmentioning

confidence: 99%

Multiwalled Carbon Nanotubes-CeO2 Nanorods: A “Nanonetwork” Modified Electrode for Detecting Trace Rifampicin

Zhang¹,

Helú

Zhang³

et al. 2020

Nanomaterials

View full text Add to dashboard Cite

Herein, a “nanonetwork” modified electrode was fabricated based on multiwalled carbon nanotubes and CeO2 nanorods. Scanning electron microscopy, X-ray powder diffraction and zeta potential were employed to characterize this electrode. Multiwalled carbon nanotubes negatively charged and CeO2 nanorods positively charged form “nanonetwork” via electrostatic interaction. The performance of the CeO2 nanorods-based electrode remarkably improved due to the introduction of multiwalled carbon nanotubes. The detection of rifampicin (RIF) was used as a model system to probe this novel electrode. The results showed a significant electrocatalytic activity for the redox reaction of RIF. Differential pulse voltammetry was used to detect rifampicin, the reduction peak current of rifampicin linear with the logarithm of their concentrations in the range of 1.0 × 10−13–1.0 × 10−6 mol/L, The linear equation is ip = 6.72 + 0. 46lgc, the detect limit is 3.4 × 10−14 mol/L (S/N = 3). Additionally, the modified electrode exhibits enduring stability, excellent reproducibility, and high selectivity. This strategy can be successfully used to detect trace rifampicin in samples with satisfactory results.

show abstract

Section: Introductionmentioning

confidence: 99%

Multiwalled Carbon Nanotubes-CeO2 Nanorods: A “Nanonetwork” Modified Electrode for Detecting Trace Rifampicin

Zhang¹,

Helú

Zhang³

et al. 2020

Nanomaterials

View full text Add to dashboard Cite

show abstract

“…This disease can be spread from one person to another by being exposed to the droplets released from patient by sneezing and/or coughing into the air. The drug use is crucial for effective healing during the 6‐months treatment . One of the most common anti‐tuberculosis agents is pyridine‐4‐carboxylic acid hydrazide, commonly known as Isoniazid (INZ), is usually administrated to inhibit the progress of clinical tuberculosis.…”

Section: Introductionmentioning

confidence: 99%

Voltammetric Determination of Isoniazid Drug in Various Matrix by Using CuO_x Decorated MW‐CNT Modified Glassy Carbon Electrode

Özdokur

2019

Electroanalysis

View full text Add to dashboard Cite

Copper oxide decorated multi‐walled carbon nanotube (MWCNT) modified glassy carbon electrode (GCE) was prepared for determination of isoniazid (INZ) in various matrices. The electrochemical behavior of INZ was tested with the aid of Cyclic Voltammetry (CV) and quantitative experiments were performed by using Linear Sweep Voltammetry (LSV). Morphological and structural characterization of the modified electrode was performed by utilizing Scanning Electron Microscopy (SEM), X‐Ray Photoelectron Spectroscopy (XPS) while electrochemical characterization was performed by using CV and Electrochemical Impedance spectroscopy (EIS). The proposed sensor exhibited well defined anodic peak at 0.30 V for INZ at pH 6.0 medium. Under the optimum conditions, a linear relation between INZ concentration and peak current was observed in the range of 2.0×10−7 to 5.0×10−5 M. Limit of detection was calculated as 1.0×10−8 M and repeatability and accuracy was found as 5.60 % and 91.0 % for 5.0 10−7 M INZ by using 3 successive measurement, respectively. Then, the analytic performance of the electrode developed was tested by analyzing commercial tablets, artificial human serum and urine samples. The results indicated that satisfactory recoveries was observed for all issue.

show abstract

“…Lower LODs were only in 18,32 , however linear ranges of those studies were narrower. In addition, the electrode preparation procedures were long and complicated especially in 17,[33][34][35] compared to the MWCNT/GC electrode used in this study.…”

Section: Determination Of Rif From Pharmaceutical Dosage Formsmentioning

confidence: 99%

“…The parameters of the validated DPV and SWV techniques for the MWCNT/GC electrode were compared with other sensors in the literature obtained for the determination of RIF both in the anodic[15][16][17][18]21,[32][33][34][35] and cathodic21,22,36- 38 directions …”

mentioning

confidence: 99%

Electrochemical Determination of Rifampicin Based on Its Oxidation UsingMultiwalled Carbon Nanotubes Modified Glassy Carbon Electrode

Kul¹

2019

tjps

View full text Add to dashboard Cite

INTRODUCTION:The aim of the study was to investigate the electrochemical behavior of rifampicin in the anodic direction using multiwalled carbon nanotube modified glassy carbon electrodes. METHODS: The anodic investigation of rifampicin was carried out with cyclic, differential pulse and square wave voltammetry techniques. The three-electrode system consisting of a glassy carbon electrode with a modification of MWCNT as working electrode, a platinum wire as counter electrode, and an Ag/AgCl electrode as reference was used for the experiments. RESULTS: The anodic process of rifampicin was irreversible and diffusion controlled. Linear responses were obtained between 0.04 and 10 µM for both techniques in acetate buffer at pH 3.5 as supporting electrolyte. Limit of detection values were 7.51 and 11.3 nM for differential pulse and square wave voltammetry techniques, respectively. The repeatability, reproducibility, precision, and accuracy of the proposed methods were also investigated. Determination of rifampicin was carried out from its pharmaceutical dosage forms and the results were compared with other electrochemical sensors and also the liquid chromatographic and spectrophotometric methods in the literature. DISCUSSION AND CONCLUSION: These validated techniques provided selective, rapid, sensitive, precise, and cheap determination of rifampicin as alternative techniques to the liquid chromatographic and spectrophotometric methods in therapeutic drug monitoring.Keywords: Rifampicin, voltammetry, multiwalled carbon nanotubes, glassy carbon electrode, pharmaceuticals GİRİŞ ve AMAÇ: Bu çalışmanın amacı, rifampisinin elektrokimyasal davranışını çok duvarlı karbon nanotüp ile modifiye edilmiş camsı karbon elektrotlar kullanarak anodik yönde incelemektir. YÖNTEM ve GEREÇLER: Rifampisinin anodik incelemesi dönüşümlü, diferansiyel puls ve kare dalga voltametri teknikleri ile yapıldı. Çalışma elektrotu olarak MWCNT'nin bir modifikasyonuna sahip camsı bir karbon elektrot, karşı elektrot olarak bir platin tel ve referans olarak bir Ag/AgCl elektrotundan oluşan üç elektrotlu sistem, deneyler için kullanıldı. BULGULAR: Rifampisin anodik süreci geri dönüşümsüzdü ve difüzyon kontrollü idi. Destek elektrolit olarak pH 3.5'te asetat tamponunda her iki teknik için de 0.04 ila 10 µM arasında doğrusal cevaplar elde edildi. Tespit limiti değerleri diferansiyel puls ve kare dalga voltametri teknikleri için sırasıyla 7.51 ve 11.3 nM olarak bulundu. Önerilen yöntemlerin tekrarlanabilirliği, tekrar üretilebilirliği, kesinliği ve doğruluğu da incelendi. Rifampisinin tayini, farmasötik dozaj formlarından yapıldı ve sonuçlar, literatürdeki diğer elektrokimyasal sensörler ve ayrıca sıvı kromatografik ve spektrofotometrik yöntemlerle karşılaştırıldı. TARTIŞMA ve SONUÇ: Bu valide edilmiş teknikler, terapötik ilaç izlemede sıvı kromatografik ve spektrofotometrik yöntemlere alternatif teknikler olarak rifampisinin seçici, hızlı, hassas, kesin ve ucuz bir şekilde tayinini sağladı.Anahtar Kelimeler: Rifampisin, voltammetri, çok duvarlı karbon nanot...

show abstract

Sensitive electrochemical determination of rifampicin using gold nanoparticles/poly-melamine nanocomposite

Abstract: Green and facile method for fabrication of a conductive polymer–Au nanocomposite platform as a novel electrochemical sensing layer for rifampicin.

Cited by 53 publications

References 34 publications

Multiwalled Carbon Nanotubes-CeO2 Nanorods: A “Nanonetwork” Modified Electrode for Detecting Trace Rifampicin

Multiwalled Carbon Nanotubes-CeO2 Nanorods: A “Nanonetwork” Modified Electrode for Detecting Trace Rifampicin

Voltammetric Determination of Isoniazid Drug in Various Matrix by Using CuO_x Decorated MW‐CNT Modified Glassy Carbon Electrode

Electrochemical Determination of Rifampicin Based on Its Oxidation UsingMultiwalled Carbon Nanotubes Modified Glassy Carbon Electrode

Contact Info

Product

Resources

About

Sensitive electrochemical determination of rifampicin using gold nanoparticles/poly-melamine nanocomposite

Abstract: Green and facile method for fabrication of a conductive polymer–Au nanocomposite platform as a novel electrochemical sensing layer for rifampicin.

Cited by 53 publications

References 34 publications

Multiwalled Carbon Nanotubes-CeO2 Nanorods: A “Nanonetwork” Modified Electrode for Detecting Trace Rifampicin

Multiwalled Carbon Nanotubes-CeO2 Nanorods: A “Nanonetwork” Modified Electrode for Detecting Trace Rifampicin

Voltammetric Determination of Isoniazid Drug in Various Matrix by Using CuOx Decorated MW‐CNT Modified Glassy Carbon Electrode

Electrochemical Determination of Rifampicin Based on Its Oxidation UsingMultiwalled Carbon Nanotubes Modified Glassy Carbon Electrode

Contact Info

Product

Resources

About

Voltammetric Determination of Isoniazid Drug in Various Matrix by Using CuO_x Decorated MW‐CNT Modified Glassy Carbon Electrode