Sensitive Quantification of Cerebellar Speech Abnormalities Using Deep Learning Models
Kyriakos Vattis,
Brandon Oubre,
Anna C. Luddy
et al.
Abstract:Objective: Objective, sensitive, and meaningful disease assessments are critical to support clinical trials and clinical care. Speech changes are one of the earliest and most evident manifestations of cerebellar ataxias. This work aims to develop models that can accurately identify and quantify clinical signs of ataxic speech. Methods: We use convolutional neural networks to capture the motor speech phenotype of cerebellar ataxia based on time and frequency partial derivatives of log-mel spectrogram representa… Show more
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