Current concerns regarding the dependability of psychological findings call for methodological developments to provide additional evidence in support of scientific conclusions. This paper highlights the value and importance of two distinct kinds of parameter uncertainty which are quantified by confidence sets (CSs) and fungible parameter estimates (FPEs; T. Lee, MacCallum, & Browne, in press); both provide essential information regarding the defensibility of scientific findings. Using the structural equation model, we introduce a general perturbation framework based on the likelihood function that unifies CSs and FPEs and sheds new light on the conceptual distinctions between them. A targeted illustration is then presented to demonstrate the factors which differentially influence CSs and FPEs, further highlighting their theoretical differences. With three empirical examples on initiating a conversation with a stranger (Bagozzi & Warshaw, 1988), posttraumatic growth of caregivers in the context of pediatric palliative care (Cadell et al., 2014), and the direct and indirect effects of spirituality on thriving among youth (Dowling et al., 2004), we illustrate how CSs and FPEs provide unique information which lead to better informed scientific conclusions. Finally, we discuss the importance of considering information afforded by CSs and FPEs in strengthening the basis of interpreting statistical results in substantive research, conclude with future research directions, and provide example OpenMx code for the computation of CSs and FPEs.Keywords: confidence sets, fungible estimates, sensitivity analysis, profile likelihood, structural equation modeling CONFIDENCE SETS AND FUNGIBLE ESTIMATES 3 Parameter uncertainty in structural equation models:Confidence sets and fungible estimates Statistical practice in psychological science is undergoing reform in response to concerns over the dependability of findings (Harlow, Mulaik, & Steiger, 2016; Open Science Collaboration, 2015;Pashler & Wagenmakers, 2012;Simmons, Nelson, & Simonsohn, 2011;Sijtsma, 2015). In response to these concerns, the reporting of effect sizes or focal parameter estimates and their confidence intervals (CIs) have been recommended as best practice (Cumming, 2014; Wilkinson & the Task Force on Statistical Inference, 1999). Confidence intervals communicate precision in estimation, providing information to researchers on whether inferences about their commensurate parameters can be drawn. Note that confidence regions (CRs) are an extension of CIs from a single parameter to a set of multiple parameters, and we use the term confidence sets (CSs) to collectively refer to CIs and CRs. Additionally, recent quantitative developments show that examining parameter sensitivity (T. Lee & MacCallum, 2015) and fungible parameter estimates (FPEs; T. Lee et al., in press;MacCallum, Browne, & Lee, 2009;Waller, 2008) can add to substantive researchers' diagnostic toolkit in terms of generating more information about the validity of their statistical results. Rel...