2024
DOI: 10.1002/nav.22239
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Sensitivity Analysis on Policy‐Augmented Graphical Hybrid Models With Shapley Value Estimation

Junkai Zhao,
Wei Xie,
Jun Luo

Abstract: Driven by the critical challenges in biomanufacturing, including high complexity and high uncertainty, we propose a comprehensive and computationally efficient sensitivity analysis framework for general nonlinear policy‐augmented knowledge graphical (pKG) hybrid models that characterize the risk‐ and science‐based understandings of underlying stochastic decision process mechanisms. The criticality of each input (i.e., random factors, policy parameters, and model parameters) is measured by applying Shapley valu… Show more

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