Sensitivity and Specificity of Electroencephalography (EEG) Among Patients Referred to an Electrophysiology Lab in Bangladesh

Chowdhury, Ahmed Hossain; Chowdhury, Rajib Nayan; Khan, Sharif Uddin; Ghose, Swapon Kumar; Wazib, Amit; Alam, Iftikher; Hasan, Atm Hasibul; Shaha, Kanol; Mahmud, Khurshid; Haque, Badrul; Habib, Mansur

doi:10.3329/jdmc.v23i2.25394

Cited by 5 publications

(6 citation statements)

References 59 publications

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“…Regarding background dominating activities, the study showed that the main dominating activities were from the parietal region of the brain, followed by occipital and temporal regions; this is inconsistent with a study in Bangladesh, which showed that the most common site of origin of epileptiform discharge was temporal lobe (28.3%). 15 About two-thirds of the patients showed epileptic discharges, almost similar results were reported in an Indian study, where more than 70% of the patients had abnormal EEG findings. 21 Among those with abnormal discharges showed significantly higher sharp slow waves and sharp waves, almost similar results were reported in another Indian study, where the sharp waves were the most predominant 15 Results of the study showed that age-related prevalence of epilepsy showed a significantly higher prevalence of the disease among those who were 20 years or above.…”

Section: Resultssupporting

confidence: 81%

“…15 About two-thirds of the patients showed epileptic discharges, almost similar results were reported in an Indian study, where more than 70% of the patients had abnormal EEG findings. 21 Among those with abnormal discharges showed significantly higher sharp slow waves and sharp waves, almost similar results were reported in another Indian study, where the sharp waves were the most predominant 15 Results of the study showed that age-related prevalence of epilepsy showed a significantly higher prevalence of the disease among those who were 20 years or above. Among them, generalized epilepsy was the most common type, and focal epilepsy was more prevalent among those aged less than 20 years.…”

Section: Resultssupporting

confidence: 81%

“…A study in Bangladesh showed a higher incidence of the disease among younger age groups, with more prevalence among males, and for most incidence studies, sex-specific differences in incidence are not statistically significant. 15 Another study in the USA revealed no significant statistical differences by age group and gender among the study participants. 20 This could be due to greater outdoor activities and more exposure to risk factors, which might expose males to a higher risk of epilepsy than females.…”

Section: Resultsmentioning

confidence: 85%

“…The most common site of origin of epileptiform discharge was temporal lobe (28.3%). 15 This could be due to the background etiology of the disease, patients' clinical features, and sensitivity and specificity of the EEG. The overall sensitivity of EEG was 67.8% (95% CI 62.19%-72.99%), and the specificity was 63.5% (95% CI 52.03%-72.18); almost similar results were reported in other studies in Bangladesh, Pakistan and Netherland.…”

Section: Resultsmentioning

confidence: 99%

“…The overall sensitivity of EEG was 67.8% (95% CI 62.19%-72.99%), and the specificity was 63.5% (95% CI 52.03%-72.18); almost similar results were reported in other studies in Bangladesh, Pakistan and Netherland. 15,16,25 The current study is the first study in the Kurdistan region and Iraq addressing sensitivity and specificity of EEG among suspected patients with epilepsy. This study has a number of limitations.…”

Section: Resultsmentioning

confidence: 99%

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Electro encephalography screening of suspected epileptic patients in Erbil City

Hummadi

2019

Zanco J. Med. Sci.

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non-epileptic patients through electroencephalography investigation and determine its relationship with certain socio-demographic and clinical characteristics. Methods: In this cross-sectional study included 400 cases (205 males and 195 females) with a mean age ± SD of 25 ± 14 years, referred to the private neurology clinic, Soran Medical Center between April 2013 and March 2017 for attacks of abnormal movements and or disturbed level of consciousness. Results: Age-related prevalence of epilepsy showed a significantly higher prevalence (P = 0.001) of the disease among those who were 20 years and more. Epileptic patients showed significantly (P = 0.001) higher sharp slow waves and sharp waves, which were mainly dominated by parietal and occipital regions of the brain. Electroencephalography finding showed higher Beta rhythm followed by Alpha and Delta rhythms (73.5%, 14.3% and 9.0%, respectively), Patients with epilepsy (generalized and focal) had shown best rhythm adoption in Beta rhythm (75.2% and 70.2%, respectively), followed by Alpha rhythm (13.2% and 14.8%, respectively). Focal to bilateral (secondary generalized) and generalized motor epilepsy were the most common diagnosis among the epileptic cases (45.4% and 43.4%, respectively). The overall sensitivity of electroencephalography was 67.8%, and specificity was 63.5%. Conclusion: The electroencephalography showed good sensitivity and specificity in diagnosing suspected epileptic patients, with interesting higher sensitivity than specificity. Not only the abnormal discharges, but the background dominating activity and the best rhythm adoption can help in the diagnosis of epilepsy.

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Section: Resultssupporting

confidence: 81%

Section: Resultssupporting

confidence: 81%

Section: Resultsmentioning

confidence: 85%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Electro encephalography screening of suspected epileptic patients in Erbil City

Hummadi

2019

Zanco J. Med. Sci.

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Outcomes of patients with nonepileptic transient neurologic symptoms after subdural hematoma evacuation

et al. 2021

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Nonepileptic, Stereotypical, and Intermittent Symptoms (NESIS) in Patients With Subdural Hematoma: Proposal for a New Clinical Entity With Therapeutic and Prognostic Implications

et al. 2019

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BACKGROUND Transient neurological symptoms (TNS) are frequent in patients with subdural hematomas (SDH) and many will receive a diagnosis of epilepsy despite a negative workup. OBJECTIVE To explore if patients with TNS and a negative epilepsy workup (cases) evolved differently than those with a positive EEG (controls), which would suggest the existence of alternative etiologies for TNS. METHODS We performed a single-center, retrospective, case-control study of patients with TNS post-SDH. The demographics and clinical and semiological features of cases and controls were compared. The outcome and response to antiepileptic drugs were also assessed and a scoring system developed to predict negative EEG. RESULTS Fifty-nine patients with SDH-associated TNS were included (39 cases and 20 controls). Demographic characteristics were comparable in both groups. Dysphasia and prolonged episodes were associated with a negative EEG. Clonic movements, impaired awareness, positive symptomatology, complete response to antiepileptic drugs, and mortality were associated with a positive EEG. Using semiological variables, we created a scoring system with a 96.6% sensitivity and 100% specificity in predicting case group patients. The differences observed between both groups support the existence of an alternative etiology to seizures in our case group. We propose the term NESIS (NonEpileptic, Stereotypical, and Intermittent Symptoms) to refer to this subgroup and hypothesize that TNS in these patients might result from cortical spreading depolarization. CONCLUSION We describe NESIS as a syndrome experienced by SDH patients with specific prognostic and therapeutic implications. Independent validation of this new entity is now required.

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Sensitivity and Specificity of Electroencephalography (EEG) Among Patients Referred to an Electrophysiology Lab in Bangladesh

Abstract: Conclusion:Our study brings out the fact that EEG has a reasonable sensitivity and specificity as a diagnostic test and the superiority being the higher specificity of EEG.

Cited by 5 publications

References 59 publications

Electro encephalography screening of suspected epileptic patients in Erbil City

Electro encephalography screening of suspected epileptic patients in Erbil City

Outcomes of patients with nonepileptic transient neurologic symptoms after subdural hematoma evacuation

Nonepileptic, Stereotypical, and Intermittent Symptoms (NESIS) in Patients With Subdural Hematoma: Proposal for a New Clinical Entity With Therapeutic and Prognostic Implications

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