Sensitivity enhancement of lateral flow assay by embedding cotton threads in paper

Zhang, Sufeng; Liu, Lina; Tang, Ruihua; Liu, Zhi; He, Xiaocong; Qu, Zhiguo; Li, Fēi

doi:10.1007/s10570-019-02677-6

Cited by 27 publications

(17 citation statements)

References 44 publications

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“…Finally, the sample passes through the CL and arrives to the absorbent pad. The sensitivity of a lateral flow assay maybe improved by decreasing the flow rate and increasing the time of the test by engineering the pad structure(Sena-Torralba et al, 2020;S.-F. Zhang et al, 2019), by optimizing the concentration of recognition element on the surface of AuNPs(Byzova et al, 2017), or by increasing the amount of the capturing antibody on the TL(Pan et al, 2018).TA B L E 1 Target bacteria and their toxins, recognition elements, and AuNPs-based tests used for detection in milk Target…”

mentioning

confidence: 99%

Rapid point‐of‐need detection of bacteria and their toxins in food using gold nanoparticles

Marin

Nikolić

Vidić

2021

Comp Rev Food Sci Food Safe

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Biosensors need to meet the rising food industry demand for sensitive, selective, safe, and fast food safety quality control. Disposable colorimetric sensors based on gold nanoparticles (AuNPs) and localized surface plasmon resonance are low-cost and easy-to-perform devices intended for rapid point-of-need measurements. Recent studies demonstrate various facile and versatile AuNPs-based analytical platforms for the detection of bacteria and their toxins in milk, meat, and other foods. In this review, we introduce the general characteristics and mechanisms of AuNPs calorimetric biosensors, and highlight optimizations needed to strengthen and improve the quality of devices for their application in food matrices.

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mentioning

confidence: 99%

Rapid point‐of‐need detection of bacteria and their toxins in food using gold nanoparticles

Marin

Nikolić

Vidić

2021

Comp Rev Food Sci Food Safe

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“…Adjustable hydrophilic cotton thread-based barriers embedded into the detection pad have also shown the ability to decrease the speed flow, allowing to reach a 4-fold enhancement in sensitivity (Fig. 3B) [18]. Compared with wax barriers, cotton thread modification is simpler, and the obtained membranes are more stable and less susceptible to suffering from interferences.…”

Section: Detection Pad Modificationmentioning

confidence: 99%

“…The advantages of this strategy are related to the more ELISA-like format assay, which [17], copyright 2014, with permission from Royal Society of Chemistry). (B) Adjustable hydrophilic cotton thread-based barriers (reprinted from [18], copyright 2019, with permission from Springer Nature). (C) Additional/retention pad (reprinted from [19], copyright 2018, with permission from Springer Nature).…”

Section: General Design/architecturementioning

confidence: 99%

Strip modification and alternative architectures for signal amplification in nanoparticle-based lateral flow assays

Díaz‐González

Escosura‐Muñiz

2021

Anal Bioanal Chem

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Nanoparticle (NP)-based lateral flow assay (LFA) technology has outstanding characteristics that make it ideal for point-of-care bioanalytical applications. However, LFAs still have important limitations, especially related to sensitivity, which is in general worse than that of other well-established bioassays such as ELISA or PCR. Many efforts have been made for enhancing the sensitivity of LFAs, mainly actuating on the nanoparticle labels and on alternative optical detection modes. However, strip pads modification for such a purpose is an incipient vast field of research. This article gives a brief overview on the recent advances proposed for signal amplification actuating on different pads and the general architecture of the LFA strips. Such strategies offer universal tools that can be adapted to any LFA, independently of the kind of sample, analyte, and label. The principles of the different strategies developed to achieve novel signal amplification and sensitive detection are discussed, and some examples of relevant approaches are highlighted, together with future prospects and challenges.

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“…These techniques can cut costs and have the potential to be used in POC settings. On the other hand, hybridization of different technologies such as paper-hydrogel [221], paper-thread [222] based technologies can be used for enhancing the diagnostic sensitivity and reduce costs. The FDA has not cleared any of these emerging products for clinical use yet.…”

Section: Future Direction and Conclusionmentioning

confidence: 99%

Dengue Detection: Advances in Diagnostic Tools from Conventional Technology to Point of Care

et al. 2021

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The dengue virus (DENV) is a vector-borne flavivirus that infects around 390 million individuals each year with 2.5 billion being in danger. Having access to testing is paramount in preventing future infections and receiving adequate treatment. Currently, there are numerous conventional methods for DENV testing, such as NS1 based antigen testing, IgM/IgG antibody testing, and Polymerase Chain Reaction (PCR). In addition, novel methods are emerging that can cut both cost and time. Such methods can be effective in rural and low-income areas throughout the world. In this paper, we discuss the structural evolution of the virus followed by a comprehensive review of current dengue detection strategies and methods that are being developed or commercialized. We also discuss the state of art biosensing technologies, evaluated their performance and outline strategies to address challenges posed by the disease. Further, we outline future guidelines for the improved usage of diagnostic tools during recurrence or future outbreaks of DENV.

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Sensitivity enhancement of lateral flow assay by embedding cotton threads in paper

Cited by 27 publications

References 44 publications

Rapid point‐of‐need detection of bacteria and their toxins in food using gold nanoparticles

Rapid point‐of‐need detection of bacteria and their toxins in food using gold nanoparticles

Strip modification and alternative architectures for signal amplification in nanoparticle-based lateral flow assays

Dengue Detection: Advances in Diagnostic Tools from Conventional Technology to Point of Care

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