Sensitivity of Klebsiella Pneumoniae Bacteria Isolated from the Urine of Patients with Urinary Tract Infections in Kirkuk City/ Iraq

Abstract

This study was conducted to investigate the presence of Klebsiella pneumoniae bacteria causing urinary tract infections among patients suffering from urinary infections, to isolate and test their antibiotic sensitivity in order to identify the effective antimicrobial agent against them. A total of 136 urine samples were collected from individuals with urinary tract infections, aged 2 to 75 years, during the period from August 6, 2023, to November 16, 2023. The samples were cultured on MacConkey agar and blood agar. A positive growth was exhibited in 65 samples, accounting for 47%, while 71 samples did not show any bacterial growth, making up 52%. Out of these, 17 isolates were identified as Klebsiella, with a positivity rate of 26%, diagnosed through microscopic, cultivation, and biochemical tests. The study results indicated that Klebsiella pneumoniae was one of the most common pathogenic causes after E.coli bacteria. The Incidence of Klebsiella was higher in females than in males, with most infections occurring in married women more than in single women. Klebsiella bacteria showed a high resistance of 100% against Gentamycin, Rifampicin, Tetracycline, Ampicillin, and Cefoxitin, while the resistance rates varied for Imipenem, Tobramycin, Trimethoprim, with 76%, 52%, and 88% respectively. The sensitivity rates ranged for Chloramphenicol, Ofloxacin, Amikacin, and Azithromycin with 41%, 35%, 11%, and 17.