Sensitivity of ternary phase diagrams of miscible polymer pairs in common solvents on traces of water: solvent-poly(ethyl acrylate)-poly(vinyl propionate) and solvent-poly(methyl acrylate)-poly(vinyl acetate) systems

Effect of temperature and moisture on the miscibility of amorphous dispersions of felodipine and poly(vinyl pyrrolidone)

“…There is clearly a large Δ χ for this system and indeed a decrease of mixing is observed when either the solid dispersions are exposed to moisture or prepared with water added to the solvent. Bhattacharyya et al46 reported a particularly interesting study where small amounts of moisture present in the organic solvent used to prepare a polymer blend resulted in phase separation. Analogous phenomena have reported for numerous binary polymer systems whereby a certain solvent induces immiscibility in polymer blends known to be compatible 47–51.…”