Sensitivity of the Sysmex XN9000 WPC-channel for detection of monoclonal B-cell populations

Differential diagnosis of lymphocytosis in routine laboratory practice: Contribution of lymphocyte parameters using the Sysmex‐XN9000 haematology analyzer

“…Flow cytometry immunophenotyping was performed to confirm the diagnosis and categorize each sample into the appropriate group. 3 For all analyses, standard operating procedures, including the use of external and daily internal quality controls were applied.…”

“…Flow cytometry immunophenotyping was performed to confirm the diagnosis and categorize each sample into the appropriate group 3 …”

“…Immunophenotyping has demonstrated to be a sensitive technology that allows precise multiparameter quantification of cells from different cell populations. The most reliable approach to accurately evaluate the performance of suspect flags from a haematology analyzer is characterization of the immunophenotype of WBCs using antigen expression on cells in normal and pathological samples, therefore flow cytometry analysis was performed to confirm the diagnosis and correctly categorize each sample 3 …”

“…The most reliable approach to accurately evaluate the performance of suspect flags from a haematology analyzer is characterization of the immunophenotype of WBCs using antigen expression on cells in normal and pathological samples, therefore flow cytometry analysis was performed to confirm the diagnosis and correctly categorize each sample. 3 In the context of lymphocytosis, the objective was to assess the need for microscopic examination and immunophenotyping by flow cytometry. It also aimed to help rapidly differentiate lymphoproliferative disorders such as chronic lymphocytic leukaemia (CLL), non-CLL lymphoproliferative disorder (NON-CLL) and non-infectious reactive lymphocytosis (REAC).…”

Flagging performance of two automated hematology analyzers in blast cell screening

“…To enable the laboratory to review specific blood specimens selectively and to significantly improve the efficiency and quality of clinical laboratories, the capability of hematology analyzers to identify and flag abnormal cells has become one of the most critical links (1). Whether there are blast cells in peripheral blood (PB) is of great value for clinical screening and monitoring of the occurrence and progression of hematological malignancies (2,3). For hematological malignancies, early diagnosis and treatment are beneficial to patients' long-term survival (4,5).…”