1975
DOI: 10.1097/00132586-197502000-00031
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Sensitivity to Intravenous Anaesthetics

Abstract: announced, as well as £32,600 as three-year support from the Department of Health for the department of psychological medicine's psycho-geriatric research programme.Eyes at the Westminster Just 250 years ago William Cheselden performed the first ophthalmic operation to be done in the then recently opened Westminster Hospital. The leading oculist of his day thus began an unbroken succession of eye surgery at the Westminster. Four years after Cheseldens' arrival Thomas Hope was also appointed oculist to the hosp… Show more

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“…However, reviewing the literature on thiopentone anaphylaxis indicates that most patients gave some history of allergy (e.g. hay fever, food sensitivity), had undergone several thiopentone anaesthetics and often showed strongly positive reactions to intradermal testing (Currie et al 1966, Carrie and Buchanan 1967, Dundee et al 1974, Strunk 1962, Unsworth 1972. Therefore it is unlikely that thiopentone was responsible, and gallamine remained the only drug to induce strongly positive reactions to intradermal testing at two dilutions, 1 in 1,000, and in 10,000, providing further confirmation of the clinical impression that the collapse was due to this drug.…”
Section: Discussionmentioning
confidence: 99%
“…However, reviewing the literature on thiopentone anaphylaxis indicates that most patients gave some history of allergy (e.g. hay fever, food sensitivity), had undergone several thiopentone anaesthetics and often showed strongly positive reactions to intradermal testing (Currie et al 1966, Carrie and Buchanan 1967, Dundee et al 1974, Strunk 1962, Unsworth 1972. Therefore it is unlikely that thiopentone was responsible, and gallamine remained the only drug to induce strongly positive reactions to intradermal testing at two dilutions, 1 in 1,000, and in 10,000, providing further confirmation of the clinical impression that the collapse was due to this drug.…”
Section: Discussionmentioning
confidence: 99%