Sensitivity to para-Phenylenediamine and Intolerance to Hydrochlorothiazide

Jacob, Sharon E.; Zapolanski, Tamar; Chayavichitsilp, Pamela

doi:10.2310/6620.2008.08019

Cited by 16 publications

(4 citation statements)

References 4 publications

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“…The compounds which cross react with PPD are para-amino benzoic acid and its derivatives, azodyes, sulfonamide, benzocaine, and para-amino salicylic acid, thiazides, and celecoxib (COX-2 inhibitors). 3,6,12,13 According to the study by Chew et al, more positive patch test was seen to PPD than sesquiterpene mix in chronic actinic dermatitis.…”

Section: Discussionmentioning

confidence: 99%

An unusual cross reactivity between hydrochlorothiazide and para-phenylenediamine: a case report

2022

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Over the last decade, the usage of hair color is gradually increasing from adolescents to the geriatric population. In the elderly population, more use of hair color due to graying of hairs exposes them to chemicals such as para-phenylenediamine (PPD). Many cases are reported regarding various manifestations of allergic contact dermatitis due to PPD compound present in hair color. It is noteworthy that, in the elderly the use of antidiabetics and antihypertensives, makes them vulnerable to cross-reaction or interaction with drugs and chemicals. We report a case that highlights the adverse reaction to hydrochlorothiazide in a PPD sensitive individual.

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Section: Discussionmentioning

confidence: 99%

An unusual cross reactivity between hydrochlorothiazide and para-phenylenediamine: a case report

2022

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“…Kontaktallergi mot parafenylendiamin kan gi kryssreaksjon overfor kjemisk beslektede stoffer, saerlig andre tekstilfargestoffer (11,12) og kurvplanteallergenet seskviterpenlakton (13). Det er også rapporter om mulig kryssreaksjon med enkelte medikamenter, som mesalazin (14), sulfonamid (15) og hydroklortiasid (16), men slike kryssreaksjoner synes å vaere dårligere dokumentert.…”

Section: Kontaktallergiunclassified

Kontaktallergi mot hennatatovering

Steinkjer¹,

Stangeland²,

Mikkelsen³

2011

Tidsskriftet

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“…Apart from that, PPD has potential toxicity which includes acute toxicity such as allergic contact dermatitis and subacute toxicity. The limit of PPD in hair dyes is 6% [6][7][8][9][10] . The oxidation of PPD on the surface and within the skin is responsible for the initiation of allergic reactions [11][12][13][14] .…”

Section: Introductionmentioning

confidence: 99%

Untitled

2024

IJPSR

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To estimate the presence of para-phenylenediamine in various commercial hair colors, a straightforward, speedy, precise investigation used High-Performance Liquid Chromatography to find PPD in henna and determine its presence. In order to do the chromatography, stationary phase Phenomenox C18 100 mm x 4.6 mm, 5µm column system was used for UV detection with a242 nm wavelength. The mobile phase Methanol with water (HPLC grade) (70:30) was used as the mobile phase for the technique, which was created and validated for the detection of PPD in samples of commercial hair color. With a run time of 7 minutes, a retention time of 2.088 seconds, and a flow rate of 0.55 ml/min, the method was validated over a broad linear range of 5-28 g/ml. The PPD content of hair colors may not exceed 6%. The procedures were approved in line with ICH guidelines.

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Sensitivity to para-Phenylenediamine and Intolerance to Hydrochlorothiazide

Cited by 16 publications

References 4 publications

An unusual cross reactivity between hydrochlorothiazide and para-phenylenediamine: a case report

An unusual cross reactivity between hydrochlorothiazide and para-phenylenediamine: a case report

Kontaktallergi mot hennatatovering

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