Sensitizing oat extracts in cosmetic creams: is there an alternative?

Vansina, Sara; Debilde, Dominique; Morren, Marie‐Anne; Goossens, An

doi:10.1111/j.1600-0536.2010.01762.x

Cited by 26 publications

(16 citation statements)

References 12 publications

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“…However, not only low-molecular chemicals but also proteins and protein-derived, that is, hydrolysed products used in skin- and hair-care products are increasingly reported in this regard: for example, oat or Avena extract [58, 59]—of which the allergenic proteins may be removed though [60]—hydrolyzed wheat protein [61]. Immediate-type reactions to protein-derived products may sometimes give rise to severe symptoms [61, 62].…”

Section: Contact Urticaria (Syndrome)mentioning

confidence: 99%

“…Immediate-type reactions to protein-derived products may sometimes give rise to severe symptoms [61, 62]. Although such reactions seem to be rare and may sometimes be irritant in nature, especially in atopic subjects, their use has given rise to controversies since subjects may perhaps get sensitized through topical preparations and develop food allergies afterwards, or vice-versa, and also in children [58–60]. …”

Section: Contact Urticaria (Syndrome)mentioning

confidence: 99%

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Contact-Allergic Reactions to Cosmetics

Goossens

2011

Journal of Allergy

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Contact-allergic reactions to cosmetics may be delayed-type reactions such as allergic and photo-allergic contact dermatitis, and more exceptionally also immediate-type reactions, that is, contact urticaria. Fragrances and preservative agents are the most important contact allergens, but reactions also occur to category-specific products such as hair dyes and other hair-care products, nail cosmetics, sunscreens, as well as to antioxidants, vehicles, emulsifiers, and, in fact, any possible cosmetic ingredient. Patch and prick testing to detect the respective culprits remains the golden standard for diagnosis, although additional tests might be useful as well. Once the specific allergens are identified, the patients should be informed of which products can be safely used in the future.

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Section: Contact Urticaria (Syndrome)mentioning

confidence: 99%

Section: Contact Urticaria (Syndrome)mentioning

confidence: 99%

Contact-Allergic Reactions to Cosmetics

Goossens

2011

Journal of Allergy

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“…48,[143][144][145] However, some cases of oat and wheat sensitization have been reported in the literature. [146][147][148] For several years, we have been developing a new extract (Dry Extract of Rhealba â Oat Plantlet) without traces of proteins to avoid the risk of allergy as far as possible. The main objective of this study was to assess the absence of sensitization risk of dry extract of oat plantlet by means of the integrated testing strategy (ITS) using several in vitro studies, and to compare the obtained results with those previously obtained in vivo.…”

Section: Introductionmentioning

confidence: 99%

Fragility of epidermis in newborns, children and adolescents

Blume-Peytavi

Tan

Tennstedt

et al. 2016

Acad Dermatol Venereol

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Within their first days of life, newborns' skin undergoes various adaptation processes needed to accommodate the transition from the wet uterine environment to the dry atmosphere. The skin of newborns and infants is considered as a physiological fragile skin, a skin with lower resistance to aggressions. Fragile skin is divided into four categories up to its origin: physiological fragile skin (age, location), pathological fragile skin (acute and chronic), circumstantial fragile skin (due to environmental extrinsic factors or intrinsic factors such as stress) and iatrogenic fragile skin. Extensive research of the past 10 years have proven evidence that at birth albeit showing a nearly perfect appearance, newborn skin is structurally and functionally immature compared to adult skin undergoing a physiological maturation process after birth at least throughout the first year of life. This article is an overview of all known data about fragility of epidermis in 'fragile populations': newborns, children and adolescents. It includes the recent pathological, pathophysiological and clinical data about fragility of epidermis in various dermatological diseases, such as atopic dermatitis, acne, rosacea, contact dermatitis, irritative dermatitis and focus on UV protection .

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“…Nowadays, skin-care products, especially in those intended to treat dry skin in atopic subjects (often children) often contain potentially sensitizing protein-containing plant extracts, and hydrolyzed proteins in particular, which may, besides delayed-type reactions, also cause IgE-mediated contact urticaria. Examples are Avena sativa (oat meal) extract [57] and hydrolyzed wheat proteins. Recently, a three-year old atopic boy was described who had probably been sensitized to hydrolyzed wheat protein contained in a moisturizer via maternal skin contact (by proxy) [58].…”

Section: Natural Ingredientsmentioning

confidence: 99%

Cosmetic Contact Allergens

Goossens

2016

Cosmetics

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This article presents trends in the frequency of cosmetics as causal factors of allergic contact dermatitis during a 26-year period in 14,911 patients patch-tested between 1990 and 2014, and discusses the cosmetic allergens identified during the last six years (2010-2015) in 603 patients out of 3105 tested. The data were retrieved from, and evaluated with, a patient database developed in-house. The results show the increasing importance of cosmetic allergies, up to 25% of the patients tested during the last five-year period. As expected, fragrance materials, preservatives, and hair dyes were the most frequent culprits, but a great variety of other allergenic ingredients were involved as well. This underlines the need of additional and extensive patch testing with the patient's products used and their ingredients.

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Sensitizing oat extracts in cosmetic creams: is there an alternative?

Cited by 26 publications

References 12 publications

Contact-Allergic Reactions to Cosmetics

Contact-Allergic Reactions to Cosmetics

Fragility of epidermis in newborns, children and adolescents

Cosmetic Contact Allergens

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