2018
DOI: 10.1007/s00520-018-4531-4
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Sensorimotor training and whole-body vibration training have the potential to reduce motor and sensory symptoms of chemotherapy-induced peripheral neuropathy—a randomized controlled pilot trial

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Cited by 81 publications
(94 citation statements)
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“…To ensure the quality of reporting WBV treatment trials biomechanical parameters such as frequency, peak-to-peak displacement or periodicity of the sessions have been defined [31] , [32] . Many findings confirm safety and feasibility as well as efficacy of low-magnitude high-frequency WBV for improving physical performance in healthy subjects as well as in adult patients with chronic diseases, chemotherapy-induced peripheral neuropathy as well as pediatric cancer patients [33] , [34] , [35] , [36] , [37] , [38] , [39] , [40] . More recently, favorable effects of WBV on quality of life, physical functioning, and fatigue were evidenced in patients with hematological malignancies [41] , [42] .…”
Section: Introductionmentioning
confidence: 59%
“…To ensure the quality of reporting WBV treatment trials biomechanical parameters such as frequency, peak-to-peak displacement or periodicity of the sessions have been defined [31] , [32] . Many findings confirm safety and feasibility as well as efficacy of low-magnitude high-frequency WBV for improving physical performance in healthy subjects as well as in adult patients with chronic diseases, chemotherapy-induced peripheral neuropathy as well as pediatric cancer patients [33] , [34] , [35] , [36] , [37] , [38] , [39] , [40] . More recently, favorable effects of WBV on quality of life, physical functioning, and fatigue were evidenced in patients with hematological malignancies [41] , [42] .…”
Section: Introductionmentioning
confidence: 59%
“…Based on pilot results, a medium effect for the primary endpoint can be expected. In this randomised, controlled pilot study,18 the FACT/GOG-Ntx sum score changed by 24% (16.8±8.1 to 12.8±7.8) after 6 weeks of WBV training in 10 oncological patients, whereas the control group remained similar. Based on this pilot study, medium effect sizes seem also a realistic and relevant estimate for several of the secondary outcomes (eg, postural balance, pain).…”
Section: Methodsmentioning
confidence: 83%
“…WBV and sensorimotor training proved feasible for patients with CIPN. In addition, both exercise groups benefited (improved reflex activity, balance control and subjective reduction of symptoms) from 6 weeks of intervention twice a week 18. We consequently intend to further investigate the potentially beneficial effects of WBV in a randomized controlled trial (RCT).…”
Section: Introductionmentioning
confidence: 99%
“…These symptoms can be classified as a motor or sensory impairments. These impairments typically include sensory axonal peripheral neuropathy ('stocking and glove' neuropathy), which is accompanied by numbness, paresthesias, ongoing/spontaneous pain hypersensitivity to mechanical and thermal stimuli in the hands and feet [17], and motor symptoms such as distal weakness, reduced or absent Achilles tendon reflexes, paresthesias, breath dysregulation, abnormal swallowing, laryngospasm, muscle cramps, jaw stiffness, visual field changes, muscle weakness, reduced balance control and insecure gait, the mechanisms of which are not fully understood [20,33,40,41].…”
Section: Symptoms Of Cipnmentioning
confidence: 99%