Sensors for Enhanced Detection of Acetone as a Potential Tool for Noninvasive Diabetes Monitoring

Rydosz, Artur

doi:10.3390/s18072298

Cited by 136 publications

(91 citation statements)

References 81 publications

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“…Patients with diabetes tend to have higher acetone levels in their breath than healthy people; hence, acetone is considered as one of the biomarkers of diabetes that can be found in exhaled breath. The exhaled acetone is usually in the range of 0.2-1.8 ppm for healthy people and in the range of 1.25-2.5 ppm for people with diabetes [83]. Recently, Yang et al [84] investigated a series of biomimetic electronic nose nanomaterials of various tungsten oxides, including WO 3 :CuO and pure CuO prepared by the facile method.…”

Section: Acetone (C 3 H 6 O)mentioning

confidence: 99%

The Use of Copper Oxide Thin Films in Gas-Sensing Applications

Rydosz

2018

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In this work, the latest achievements in the field of copper oxide thin film gas sensors are presented and discussed. Several methods and deposition techniques are shown with their advantages and disadvantages for commercial applications. Recently, CuO thin film gas sensors have been studied to detect various compounds, such as: nitrogen oxides, carbon oxides, hydrogen sulfide, ammonia, as well as several volatile organic compounds in many different applications, e.g., agriculture. The CuO thin film gas sensors exhibited high 3-S parameters (sensitivity, selectivity, and stability). Furthermore, the possibility to function at room temperature with long-term stability was proven as well, which makes this material very attractive in gas-sensing applications, including exhaled breath analysis.

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Section: Acetone (C 3 H 6 O)mentioning

confidence: 99%

The Use of Copper Oxide Thin Films in Gas-Sensing Applications

Rydosz

2018

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114

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“…As an example of the variability of results even for a same type of sensor, let us refer to acetone gas sensors, which are of particular interest for diabetes monitoring through the analysis of the human exhaled breath. Table 3 presents the results achieved with the two 3D PhCs listed in Table 1 and with other metal-oxide based sensors [62]. It appears clearly that the LOD is quite different among different sensors, and that the performance of the two PhC sensors is better than most of the other sensors.…”

Section: Photonic Crystals For Chemical Sensingmentioning

confidence: 99%

Photonic Crystal Stimuli-Responsive Chromatic Sensors: A Short Review

et al. 2020

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Photonic crystals (PhC) are spatially ordered structures with lattice parameters comparable to the wavelength of propagating light. Their geometrical and refractive index features lead to an energy band structure for photons, which may allow or forbid the propagation of electromagnetic waves in a limited frequency range. These unique properties have attracted much attention for both theoretical and applied research. Devices such as high-reflection omnidirectional mirrors, low-loss waveguides, and high- and low-reflection coatings have been demonstrated, and several application areas have been explored, from optical communications and color displays to energy harvest and sensors. In this latter area, photonic crystal fibers (PCF) have proven to be very suitable for the development of highly performing sensors, but one-dimensional (1D), two-dimensional (2D) and three-dimensional (3D) PhCs have been successfully employed, too. The working principle of most PhC sensors is based on the fact that any physical phenomenon which affects the periodicity and the refractive index of the PhC structure induces changes in the intensity and spectral characteristics of the reflected, transmitted or diffracted light; thus, optical measurements allow one to sense, for instance, temperature, pressure, strain, chemical parameters, like pH and ionic strength, and the presence of chemical or biological elements. In the present article, after a brief general introduction, we present a review of the state of the art of PhC sensors, with particular reference to our own results in the field of mechanochromic sensors. We believe that PhC sensors based on changes of structural color and mechanochromic effect are able to provide a promising, technologically simple, low-cost platform for further developing devices and functionalities.

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“…The gas-sensing setup was previously described in [51,52,56]. Briefly, the developed sensors (Figure 2a,b) with various copper oxides serve as the gas-sensitive layers, which were placed in the quartz-tube oven, and the target gas at various concentrations was introduced.…”

Section: Gas-sensing Setupmentioning

confidence: 99%

“…In this paper, the investigation provides results on copper oxides deposited by a commercially available glancing angle deposition system (most papers present only the investigation on homemade GLAD manipulators, which reduce the possibility of repeating the results) at various conditions. The deposited thin films were used as gas-sensitive layers for sub-ppm acetone detection, which is recognized to be a biomarker of diabetes present in the breath [51][52][53][54][55][56].…”

Section: Introductionmentioning

confidence: 99%

GLAD Magnetron Sputtered Ultra-Thin Copper Oxide Films for Gas-Sensing Application

et al. 2020

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Copper oxide (CuO) ultra-thin films were obtained using magnetron sputtering technology with glancing angle deposition technique (GLAD) in a reactive mode by sputtering copper target in pure argon. The substrate tilt angle varied from 45 to 85° and 0°, and the sample rotation at a speed of 20 rpm was stabilized by the GLAD manipulator. After deposition, the films were annealed at 400 °C/4 h in air. The CuO ultra-thin film structure, morphology, and optical properties were assessed by X-ray diffraction (XRD), energy-dispersive X-ray spectroscopy (EDX), X-ray reflectivity (XRR), and optical spectroscopy. The thickness of the films was measured post-process using a profilometer. The obtained copper oxide structures were also investigated as gas-sensitive materials after exposure to acetone in the sub-ppm range. After deposition, gas-sensing measurements were performed at 300, 350, and 400 °C and 50% relative humidity (RH) level. We found that the sensitivity of the device is related to the thickness of CuO thin films, whereas the best results are obtained with an 8 nm thick sample.

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Sensors for Enhanced Detection of Acetone as a Potential Tool for Noninvasive Diabetes Monitoring

Cited by 136 publications

References 81 publications

The Use of Copper Oxide Thin Films in Gas-Sensing Applications

The Use of Copper Oxide Thin Films in Gas-Sensing Applications

Photonic Crystal Stimuli-Responsive Chromatic Sensors: A Short Review

GLAD Magnetron Sputtered Ultra-Thin Copper Oxide Films for Gas-Sensing Application

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