A general mass transfer based model was developed for analyzing volatile organic compound (VOC) emissions from dry multi-layer building materials with two emission surfaces. This model adds to an earlier multi-layer model by considering chemical reactions within the materials. Consequently, it can be used to analyze the effect of these chemical reactions on removing VOCs, and for characterizing secondary VOC emissions from the building material. The model was validated with literature data and our experimental results. Some typical secondary emissions were analyzed using this model, and obviously differed from the primary emissions. The model is a useful tool for predicting, analyzing and "designing" the VOC emission characteristics, including secondary emissions, of building materials. Because the majority of people spend most of their time indoors, indoor air quality is of concern [1]. In many buildings without adequate ventilation and with high loads of indoor materials and products, volatile organic compound (VOC) concentrations may be high enough to cause sick building syndrome (SBS). SBS presents with symptoms such as headache, eye, nose, or throat irritation, dry cough, dizziness and nausea, difficulty concentrating, and tiredness [2]. Dry building materials are the main sources of VOCs indoors. Therefore, building material research and industries have focused on control of VOC emissions from building materials and production of low VOC emission materials. The estimation of VOC emissions from dry building materials is also an important issue for many building designers [3]. Models for analyzing VOC emissions from these materials are useful for addressing these problems. VOC emission models in the literature fall into two general categories [4]: empirical or semi-empirical models *Corresponding author (email: wangxinke@mail.xjtu.edu.cn) [5][6][7], and mass transfer based models [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27]. The former are often simple and easy to use and their parameters are determined by fitting experimental data to the predefined model. However, they are generally unable to provide mechanistic insight, and it is difficult to scale the results from test conditions to practical conditions. In contrast, mass transfer based models can describe VOC mass transfer mechanisms or processes, and their parameters have clear physical meaning. These models can be used to predict VOC emissions for a wide range of conditions using known physical parameters. The mass transfer model developed by Little et al. [8] is considered the first mass transfer model for analyzing VOC emissions from dry building materials. Many researchers subsequently developed various mass transfer based models to describe more complicated problems, such as emissions from one-[9-15], two-[16], or multi-layer materials [17][18][19][20][21], materials with two emission surfaces [22], and porous materials [23][24][25][26][27]. Secondary VOC emissions from building materials are recognized as an impo...