Objective: Sexual dysfunction is frequently reported as a side effect of many antidepressant medications. As a result, for those depressed patients to whom sexual desire is important, psychological treatment may be a better intervention. Thus, the present study aimed to determine the possible changes in sexual desire following psychological treatments in depression, when focus of therapy is not on sexual function.Methods: This is a quasi-experimental study, which was conducted in Tehran, Iran. A total of 281 depressed patients in the remission phase underwent psychological treatments, either cognitive behavioral therapy (CBT, n=131) or mindfulness-based cognitive therapy (MBCT, n=150). The therapy did not focus on any aspect of sexual function. Using a single item measure before and after treatment, sexual desire of the patients was categorized into intact, mild, moderate, or severe decline. A total of 255 participants completed the study questionnaires and were randomly assigned to CBT (122) and MBCT groups (133). Before therapy, 128(50.2%) participants were categorized in intact sexual desire group, 73(28.6%) in mild sexual desire dysfunction group, 40(15.7%) in moderate sexual desire dysfunction group, and 14(5.5%) in severe sexual desire dysfunction group. Logistic regression was used for analyzing the data by SPSS-16.
Results
Conclusion:CBT might be superior to MBCT in improving sexual desire in patients with depression. Further studies using validated sexual function questionnaires are necessary.