Sensory gating deficits during the mid-latency phase of information processing in medicated schizophrenia patients

Effect of Homobaric Pure Oxygen on Sensory Gating in the Human Brain

“…The larger differences in D(S1 -S2) reflect stronger sensory gating effect. Recently, the concept of sensory gating has been expanded and referred to other AEP components, such as the N100 (Boutros et al 2004;Brockhaus-Dumke et al 2008). Consistent with these previous studies, our results showed the brain responses as a multi-stage process (Boutros et al 1999).…”

The neuropsychological and neurophysiological profile of women with pseudoseizure

“…P50 studies on patient groups with schizophrenia, bipolar affective disorder, panic disorder, obsessive compulsive disorder and depression have revealed worse gating than the control groups [16,[35][36][37][38][39][40][41]. Gating was also subnormal in our pseudoseizure patient group as in other psychiatric disorders.…”

α4β2 Nicotinic receptor stimulation contributes to the effects of nicotine in the DBA/2 mouse model of sensory gating

“…In addition to P50 sensory gating deficits, schizophrenic patients and first-order relatives express clinical signs of sustained attention and cognitive deficits (Chen et al 2004;Erwin et al 1998). Task-independent N40 (rodents) or P50 (humans) waves of the auditory EP are thought to be related to the automatic sensory processing function referred to as preattention (Boutros et al 2004;Ellenbroek 2004). Schizophrenic patients not only have high T:C ratios, but are also reported to express lower-amplitude P50 responses to conditioning stimuli (CAMP), compared to those of normal subjects (Adler et al 1982;Boutros et al 1991;Clementz et al 1997;Clementz and Blumenfeld 2001;Jin et al 1997;Reite et al 1988).…”